Fine‐needle aspiration cytology of metastatic breast tumor originating from leukemia

Hiroyuki Miura*, Chimori Konaka, Norihiko Kawate, Harubumi Kato, Reiko Miura, Yoshiro Ebihara

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Two cases of metastatic breast tumor originating from leukemia are reported. Fine‐needle aspiration (FNA) specimens showed a large number of isolated small‐to‐medium‐sized atypical lymphocytic cells. It is difficult to distinguish metastatic breast tumors and primary breast cancers by physical findings alone. FNA cytology is an effective method for qualitative diagnosis. When atypical lymphocytic cells are obtained in aspiration materials of the breast, past history and general examination are necessary for diagnosis. In some cases of leukemia with breast involvement, good outcomes are obtained. Therefore, earlier detection is necessary in order to begin suitable therapy earlier and to avoid unnecessary excisional biopsy in patients with leukemia and breast tumors. To achieve this it is also necessary to first take into consideration the possibility of metastasis or infiltration of leukemia, and second to prepare two types of specimen for Papanicolaou stain and Giemsa stain before operation. © 1992 Wiley‐Liss, Inc.

Original languageEnglish
Pages (from-to)605-608
Number of pages4
JournalDiagnostic cytopathology
Issue number6
Publication statusPublished - 1992 Nov
Externally publishedYes


  • Acute lymphocytic leukemia
  • Chronic myelocytic leukemia
  • Metastasis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology


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