Functionalized carbon microarrays platform for high sensitive detection of HIV-Tat peptide

Varun Penmatsa; Ruslinda A. Rahim; Hiroshi Kawarada; Chunlei Wang

doi:10.1039/c5ra10214f

Functionalized carbon microarrays platform for high sensitive detection of HIV-Tat peptide

Varun Penmatsa^*, Ruslinda A. Rahim, Hiroshi Kawarada, Chunlei Wang

^*Corresponding author for this work

School of Fundamental Science and Engineering

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

The detection of HIV disease at an early stage has significant clinical implications. We report the detection of HIV-TAT peptide on a functionalized three-dimensional carbon micropillar array platform. The sensor showed a linear relationship between HIV-TAT concentration and fluorescence intensity in the sub-nanomolar range with a detection limit of 50 pmol.

Original language	English
Pages (from-to)	65042-65047
Number of pages	6
Journal	RSC Advances
Volume	5
Issue number	80
DOIs	https://doi.org/10.1039/c5ra10214f
Publication status	Published - 2015 Jul 24

ASJC Scopus subject areas

Chemistry(all)
Chemical Engineering(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1039/c5ra10214f

Cite this

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title = "Functionalized carbon microarrays platform for high sensitive detection of HIV-Tat peptide",

abstract = "The detection of HIV disease at an early stage has significant clinical implications. We report the detection of HIV-TAT peptide on a functionalized three-dimensional carbon micropillar array platform. The sensor showed a linear relationship between HIV-TAT concentration and fluorescence intensity in the sub-nanomolar range with a detection limit of 50 pmol.",

author = "Varun Penmatsa and Rahim, {Ruslinda A.} and Hiroshi Kawarada and Chunlei Wang",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2015.",

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AU - Penmatsa, Varun

AU - Rahim, Ruslinda A.

AU - Kawarada, Hiroshi

AU - Wang, Chunlei

PY - 2015/7/24

Y1 - 2015/7/24

N2 - The detection of HIV disease at an early stage has significant clinical implications. We report the detection of HIV-TAT peptide on a functionalized three-dimensional carbon micropillar array platform. The sensor showed a linear relationship between HIV-TAT concentration and fluorescence intensity in the sub-nanomolar range with a detection limit of 50 pmol.

AB - The detection of HIV disease at an early stage has significant clinical implications. We report the detection of HIV-TAT peptide on a functionalized three-dimensional carbon micropillar array platform. The sensor showed a linear relationship between HIV-TAT concentration and fluorescence intensity in the sub-nanomolar range with a detection limit of 50 pmol.

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DO - 10.1039/c5ra10214f

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Functionalized carbon microarrays platform for high sensitive detection of HIV-Tat peptide

Abstract

ASJC Scopus subject areas

UN SDGs

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