Gas dispersion in a model pulmonary bifurcation during oscillatory flow

M. Nishida*, Y. Inaba, K. Tanishita

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

In order to clarify the gas transport process in high-frequency oscillation, we measured the axial velocity profile and the axial effective diffusivity in a single asymmetric bifurcating tube, based on the Hotsfield airway model, with sinusoidally oscillatory flow. The axial velocity profiles were measured using a laser-Doppler velocimeter, and the effective diffusivities were evaluated using a simple bolus injection method. The axial velocity profile was found to be nonuniform, promoting axial gas dispersion by the spread of the concentration profile and lateral mixing. The geometric asymmetry of the bifurcation was responsible for the difference in gas transport between the main bronchi. The axial gas transport in the left main bronchus was 2.3 times as large as that of the straight tube, whereas the gas transport in the right main bronchus was slightly larger than that of the straight tube. Thus localized variation in gas transport characterized the heterogeneous respiratory function of the lung.

Original languageEnglish
Pages (from-to)309-316
Number of pages8
JournalJournal of Biomechanical Engineering
Volume119
Issue number3
Publication statusPublished - 1997 Aug
Externally publishedYes

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biophysics

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