TY - JOUR
T1 - Generation of phenoxy radicals by methemoglobin-hydrogen peroxide studied by electron paramagnetic resonance
AU - Shiga, Takeshi
AU - Imaizumi, Kazuhiko
PY - 1973
Y1 - 1973
N2 - The free radical intermediates of phenol derivatives, produced by the methemoglobin-hydrogen peroxide system at pH 5 and 7, are detected by electron paramagnetic resonance equipped with a continuous-flow apparatus. All the radicals from phenols are the phenoxy radicals, as identified by analyzing the observed hyperfine structures of the spectra with the aid of SCF-LCAO MO calculations. Comparing with the reaction of Fenton's reagent, it is concluded that free OH radical, even if it exists, is not liberated into the solution in the methemoglobin-hydrogen peroxide system.
AB - The free radical intermediates of phenol derivatives, produced by the methemoglobin-hydrogen peroxide system at pH 5 and 7, are detected by electron paramagnetic resonance equipped with a continuous-flow apparatus. All the radicals from phenols are the phenoxy radicals, as identified by analyzing the observed hyperfine structures of the spectra with the aid of SCF-LCAO MO calculations. Comparing with the reaction of Fenton's reagent, it is concluded that free OH radical, even if it exists, is not liberated into the solution in the methemoglobin-hydrogen peroxide system.
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U2 - 10.1016/0003-9861(73)90006-4
DO - 10.1016/0003-9861(73)90006-4
M3 - Article
C2 - 4348007
AN - SCOPUS:0015581011
SN - 0003-9861
VL - 154
SP - 540
EP - 547
JO - Archives of Biochemistry and Biophysics
JF - Archives of Biochemistry and Biophysics
IS - 2
ER -