TY - GEN
T1 - Hemodynamic effects of pressure-volume relation in the atrial contraction model on the total artificial heart using centrifugal blood pumps
AU - Shiga, Takuya
AU - Kuroda, Takehito
AU - Tsuboko, Yusuke
AU - Miura, Hidekazu
AU - Shiraishi, Yasuyuki
AU - Yambe, Tomoyuki
PY - 2013
Y1 - 2013
N2 - Hemodynamic effects of atrial contraction with centrifugal pump type total artificial heart is unknown. In this study, we simulated an atrial contraction in a mock model. By the driving condition with higher pressure in the mock atrial model, the load during atrial contraction increased. Based on these findings, we examined atrial contraction in the animal using adult goats. Prior to the measurement, we installed a centrifugal-type ventricular assist device (VADs), and then clamped both ventricles. We measured the hemodynamic data without ventricular contractile functions in order to obtain the effect of atrial contraction on hemodynamics under the condition of the total artificial heart (TAH) circulatory support model. We could estimate the heart rate by revolution number and voltage of pumps. There might be a possibility that we could regulate autonomic nervous response with the control of cardiac output.
AB - Hemodynamic effects of atrial contraction with centrifugal pump type total artificial heart is unknown. In this study, we simulated an atrial contraction in a mock model. By the driving condition with higher pressure in the mock atrial model, the load during atrial contraction increased. Based on these findings, we examined atrial contraction in the animal using adult goats. Prior to the measurement, we installed a centrifugal-type ventricular assist device (VADs), and then clamped both ventricles. We measured the hemodynamic data without ventricular contractile functions in order to obtain the effect of atrial contraction on hemodynamics under the condition of the total artificial heart (TAH) circulatory support model. We could estimate the heart rate by revolution number and voltage of pumps. There might be a possibility that we could regulate autonomic nervous response with the control of cardiac output.
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U2 - 10.1109/EMBC.2013.6609875
DO - 10.1109/EMBC.2013.6609875
M3 - Conference contribution
C2 - 24110062
AN - SCOPUS:84886554761
SN - 9781457702167
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 1815
EP - 1818
BT - 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
T2 - 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Y2 - 3 July 2013 through 7 July 2013
ER -