Hepatoprotective effect of a hot-water extract from the edible thorny oyster Spondylus varius on carbon tetrachloride-induced liver injury in mice

Tomoyuki Koyama; Ritsu Chounan; Daisuke Uemura; Kohji Yamaguchi; Kazunaga Yazawa

doi:10.1271/bbb.70.729

Hepatoprotective effect of a hot-water extract from the edible thorny oyster Spondylus varius on carbon tetrachloride-induced liver injury in mice

Tomoyuki Koyama, Ritsu Chounan, Daisuke Uemura^*, Kohji Yamaguchi, Kazunaga Yazawa

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

The edible thorny oyster, Spondylus varius (Mizuirishoujou), was found to suppress the carbon tetrachloride-induced increase in serum aspartate and alanine aminotransferase activities in mice. Significant suppressive effects on these enzyme activities were found in the fraction eluted with 75% ethanol from polystyrene gel in a dose-dependent manner. These results suggest that S. varius exerts a protective effect against liver injury.

Original language	English
Pages (from-to)	729-731
Number of pages	3
Journal	Bioscience, Biotechnology and Biochemistry
Volume	70
Issue number	3
DOIs	https://doi.org/10.1271/bbb.70.729
Publication status	Published - 2006
Externally published	Yes

Keywords

Carbon tetrachloride
Functional food
Hepatoprotective effect
Spondylus varius
Thorny oyster

ASJC Scopus subject areas

Bioengineering
Biotechnology
Biochemistry
Biochemistry, Genetics and Molecular Biology(all)
Chemistry (miscellaneous)
Applied Microbiology and Biotechnology
Food Science

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10.1271/bbb.70.729

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abstract = "The edible thorny oyster, Spondylus varius (Mizuirishoujou), was found to suppress the carbon tetrachloride-induced increase in serum aspartate and alanine aminotransferase activities in mice. Significant suppressive effects on these enzyme activities were found in the fraction eluted with 75% ethanol from polystyrene gel in a dose-dependent manner. These results suggest that S. varius exerts a protective effect against liver injury.",

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AU - Koyama, Tomoyuki

AU - Chounan, Ritsu

AU - Uemura, Daisuke

AU - Yamaguchi, Kohji

AU - Yazawa, Kazunaga

PY - 2006

Y1 - 2006

N2 - The edible thorny oyster, Spondylus varius (Mizuirishoujou), was found to suppress the carbon tetrachloride-induced increase in serum aspartate and alanine aminotransferase activities in mice. Significant suppressive effects on these enzyme activities were found in the fraction eluted with 75% ethanol from polystyrene gel in a dose-dependent manner. These results suggest that S. varius exerts a protective effect against liver injury.

AB - The edible thorny oyster, Spondylus varius (Mizuirishoujou), was found to suppress the carbon tetrachloride-induced increase in serum aspartate and alanine aminotransferase activities in mice. Significant suppressive effects on these enzyme activities were found in the fraction eluted with 75% ethanol from polystyrene gel in a dose-dependent manner. These results suggest that S. varius exerts a protective effect against liver injury.

KW - Carbon tetrachloride

KW - Functional food

KW - Hepatoprotective effect

KW - Spondylus varius

KW - Thorny oyster

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Hepatoprotective effect of a hot-water extract from the edible thorny oyster Spondylus varius on carbon tetrachloride-induced liver injury in mice

Abstract

Keywords

ASJC Scopus subject areas

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