Highly controllable three-dimensional sheath flow device for fabrication of artificial capillary vessels

J. Ito; R. Sekine; Donghyun Yoon; Y. Nakamura; H. Oku; H. Nansai; T. Chikasawa; T. Goto; Tetsushi Sekiguchi; Naoya Takeda; Shuichi Shoji

doi:10.1109/MEMSYS.2015.7050996

Highly controllable three-dimensional sheath flow device for fabrication of artificial capillary vessels

J. Ito, R. Sekine, Donghyun Yoon, Y. Nakamura, H. Oku, H. Nansai, T. Chikasawa, T. Goto, Tetsushi Sekiguchi, Naoya Takeda, Shuichi Shoji

Research Organization for Nano & Life Innovation

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This paper reports a highly controllable three-dimensional (3D) sheath flow device for fabrication of artificial capillary vessels. Three step sheath injection type 3D flow device which realizes wide core and sheath structure variations by simply flow rate control was applied to fabricate double-layer coaxial Core-Sheath microfibers applicable for long micro capillary vessels by aligning and cultivating vascular endothelial cells. As a result, about a 3-centimeter-long microfiber which has the vascular endothelial cells fused mutually in the center was successfully formed after three days culture.

Original language	English
Title of host publication	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	480-483
Number of pages	4
Volume	2015-February
Edition	February
DOIs	https://doi.org/10.1109/MEMSYS.2015.7050996
Publication status	Published - 2015 Feb 26
Event	2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal Duration: 2015 Jan 18 → 2015 Jan 22

Other

Other	2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015
Country/Territory	Portugal
City	Estoril
Period	15/1/18 → 15/1/22

ASJC Scopus subject areas

Electrical and Electronic Engineering
Mechanical Engineering
Condensed Matter Physics
Electronic, Optical and Magnetic Materials

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10.1109/MEMSYS.2015.7050996

Cite this

Ito, J., Sekine, R., Yoon, D., Nakamura, Y., Oku, H., Nansai, H., Chikasawa, T., Goto, T., Sekiguchi, T., Takeda, N., & Shoji, S. (2015). Highly controllable three-dimensional sheath flow device for fabrication of artificial capillary vessels. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) (February ed., Vol. 2015-February, pp. 480-483). Article 7050996 Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MEMSYS.2015.7050996

Highly controllable three-dimensional sheath flow device for fabrication of artificial capillary vessels. / Ito, J.; Sekine, R.; Yoon, Donghyun et al.
Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). Vol. 2015-February February. ed. Institute of Electrical and Electronics Engineers Inc., 2015. p. 480-483 7050996.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Ito, J, Sekine, R, Yoon, D, Nakamura, Y, Oku, H, Nansai, H, Chikasawa, T, Goto, T, Sekiguchi, T, Takeda, N & Shoji, S 2015, Highly controllable three-dimensional sheath flow device for fabrication of artificial capillary vessels. in Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). February edn, vol. 2015-February, 7050996, Institute of Electrical and Electronics Engineers Inc., pp. 480-483, 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015, Estoril, Portugal, 15/1/18. https://doi.org/10.1109/MEMSYS.2015.7050996

Ito J, Sekine R, Yoon D, Nakamura Y, Oku H, Nansai H et al. Highly controllable three-dimensional sheath flow device for fabrication of artificial capillary vessels. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). February ed. Vol. 2015-February. Institute of Electrical and Electronics Engineers Inc. 2015. p. 480-483. 7050996 doi: 10.1109/MEMSYS.2015.7050996

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abstract = "This paper reports a highly controllable three-dimensional (3D) sheath flow device for fabrication of artificial capillary vessels. Three step sheath injection type 3D flow device which realizes wide core and sheath structure variations by simply flow rate control was applied to fabricate double-layer coaxial Core-Sheath microfibers applicable for long micro capillary vessels by aligning and cultivating vascular endothelial cells. As a result, about a 3-centimeter-long microfiber which has the vascular endothelial cells fused mutually in the center was successfully formed after three days culture.",

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AU - Ito, J.

AU - Sekine, R.

AU - Yoon, Donghyun

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AU - Nansai, H.

AU - Chikasawa, T.

AU - Goto, T.

AU - Sekiguchi, Tetsushi

AU - Takeda, Naoya

AU - Shoji, Shuichi

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N2 - This paper reports a highly controllable three-dimensional (3D) sheath flow device for fabrication of artificial capillary vessels. Three step sheath injection type 3D flow device which realizes wide core and sheath structure variations by simply flow rate control was applied to fabricate double-layer coaxial Core-Sheath microfibers applicable for long micro capillary vessels by aligning and cultivating vascular endothelial cells. As a result, about a 3-centimeter-long microfiber which has the vascular endothelial cells fused mutually in the center was successfully formed after three days culture.

AB - This paper reports a highly controllable three-dimensional (3D) sheath flow device for fabrication of artificial capillary vessels. Three step sheath injection type 3D flow device which realizes wide core and sheath structure variations by simply flow rate control was applied to fabricate double-layer coaxial Core-Sheath microfibers applicable for long micro capillary vessels by aligning and cultivating vascular endothelial cells. As a result, about a 3-centimeter-long microfiber which has the vascular endothelial cells fused mutually in the center was successfully formed after three days culture.

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Highly controllable three-dimensional sheath flow device for fabrication of artificial capillary vessels

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