Hormone and oxidative stress response during recovery on normoxia after hypoxic resistance exercise

Ryosuke Fujii*, Nobuhiro Nakamura, Takuji Kawamura, Isao Muraoka

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Various studies have been conducted on resistance exercise in a hypoxic environment. However, there are no studies examining differences in the recovery process environment. The aim of this study was to examine the effect of exposure to a normoxic environment after hypoxic resistance exercise on hormone and oxidative stress responses. METHODS: Eight male subjects performed the following trials: 1) resistance exercise and recovery under a normoxic environment (NN); 2) resistance exercise and recovery under a hypoxic environment (HH); and 3) resistance exercise under a hypoxic environment and recovery under a normoxic environment (HN). Before and after exercise, arterial oxygen saturation (SpO2), blood lactate, growth hormone (GH), testosterone (TE), cortisol, malondialdehyde (MDA), carbonylated protein (PC), and total antioxidant capacity (TAC) were measured. RESUlTS: SpO2 showed significantly lower values after resistance exercise in the HH and HN trials compared to the NN trial. Blood lactate and GH concentrations were significantly higher after exercise in all trials, but there was no difference among the trials. TE showed significantly higher values immediately after exercise, but there was no difference among the trials. Cortisol was significantly higher in the recovery phase compared to pre-exercise, and significantly higher in the HH and HN trials (P<0.05) than in the NN trial. PC and TAC did not change significantly. MDA showed a significantly lower value at 30 minutes post-exercise (P<0.05) compared to before exercise. CONClUSIONS: This study suggested that exposure to a normoxic environment after the end of hypoxic resistance exercise does not affect the hormonal and oxidative stress responses in blood.

Original languageEnglish
Pages (from-to)432-438
Number of pages7
JournalGazzetta Medica Italiana Archivio per le Scienze Mediche
Volume181
Issue number6
DOIs
Publication statusPublished - 2022 Jun
Externally publishedYes

Keywords

  • Hormones
  • Hypoxia
  • Oxidative stress
  • Resistance training

ASJC Scopus subject areas

  • Medicine(all)

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