Hydroxyapatite containing immobilized collagen and fibronectin promotes bone regeneration

Tomonori Matsuno; Eiji Uchimura; Tadao Ohno; Tazuko Satoh; Yu Sogo; Atsuo Ito; Atsushi Yamazaki; Yusuke Ishikawa; Nao Kondo; Noboru Ichinose

doi:10.1016/j.ics.2005.06.011

Hydroxyapatite containing immobilized collagen and fibronectin promotes bone regeneration

Tomonori Matsuno^*, Eiji Uchimura, Tadao Ohno, Tazuko Satoh, Yu Sogo, Atsuo Ito, Atsushi Yamazaki, Yusuke Ishikawa, Nao Kondo, Noboru Ichinose

^*Corresponding author for this work

School of Creative Science and Engineering

Research output: Contribution to journal › Review article › peer-review

7 Citations (Scopus)

Abstract

Hydroxyapatite (HA) is often used for bone tissue engineering. In this study, we evaluated a novel method for preparing HA containing immobilized collagen and fibronectin (HICF). We examined the ability of this material to promote bone regeneration in vitro and in vivo. Cell pseudopodia were grown on a HICF disk in vitro. Numerous points of new bone formation were observed around HICF granules at 4 weeks in vivo. These results indicate that HICF provides a surface that promotes bone regeneration.

Original language	English
Pages (from-to)	330-331
Number of pages	2
Journal	International Congress Series
Volume	1284
DOIs	https://doi.org/10.1016/j.ics.2005.06.011
Publication status	Published - 2005 Sept

Keywords

Bone regeneration
Collagen
Fibronectin
Hydroxyapatite
Immobilize

ASJC Scopus subject areas

Medicine(all)

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10.1016/j.ics.2005.06.011

Cite this

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title = "Hydroxyapatite containing immobilized collagen and fibronectin promotes bone regeneration",

abstract = "Hydroxyapatite (HA) is often used for bone tissue engineering. In this study, we evaluated a novel method for preparing HA containing immobilized collagen and fibronectin (HICF). We examined the ability of this material to promote bone regeneration in vitro and in vivo. Cell pseudopodia were grown on a HICF disk in vitro. Numerous points of new bone formation were observed around HICF granules at 4 weeks in vivo. These results indicate that HICF provides a surface that promotes bone regeneration.",

keywords = "Bone regeneration, Collagen, Fibronectin, Hydroxyapatite, Immobilize",

author = "Tomonori Matsuno and Eiji Uchimura and Tadao Ohno and Tazuko Satoh and Yu Sogo and Atsuo Ito and Atsushi Yamazaki and Yusuke Ishikawa and Nao Kondo and Noboru Ichinose",

year = "2005",

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doi = "10.1016/j.ics.2005.06.011",

language = "English",

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TY - JOUR

T1 - Hydroxyapatite containing immobilized collagen and fibronectin promotes bone regeneration

AU - Matsuno, Tomonori

AU - Uchimura, Eiji

AU - Ohno, Tadao

AU - Satoh, Tazuko

AU - Sogo, Yu

AU - Ito, Atsuo

AU - Yamazaki, Atsushi

AU - Ishikawa, Yusuke

AU - Kondo, Nao

AU - Ichinose, Noboru

PY - 2005/9

Y1 - 2005/9

N2 - Hydroxyapatite (HA) is often used for bone tissue engineering. In this study, we evaluated a novel method for preparing HA containing immobilized collagen and fibronectin (HICF). We examined the ability of this material to promote bone regeneration in vitro and in vivo. Cell pseudopodia were grown on a HICF disk in vitro. Numerous points of new bone formation were observed around HICF granules at 4 weeks in vivo. These results indicate that HICF provides a surface that promotes bone regeneration.

AB - Hydroxyapatite (HA) is often used for bone tissue engineering. In this study, we evaluated a novel method for preparing HA containing immobilized collagen and fibronectin (HICF). We examined the ability of this material to promote bone regeneration in vitro and in vivo. Cell pseudopodia were grown on a HICF disk in vitro. Numerous points of new bone formation were observed around HICF granules at 4 weeks in vivo. These results indicate that HICF provides a surface that promotes bone regeneration.

KW - Bone regeneration

KW - Collagen

KW - Fibronectin

KW - Hydroxyapatite

KW - Immobilize

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U2 - 10.1016/j.ics.2005.06.011

DO - 10.1016/j.ics.2005.06.011

M3 - Review article

AN - SCOPUS:33646444896

SN - 0531-5131

VL - 1284

SP - 330

EP - 331

JO - International Congress Series

JF - International Congress Series

ER -

Hydroxyapatite containing immobilized collagen and fibronectin promotes bone regeneration

Abstract

Keywords

ASJC Scopus subject areas

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