In vitro calcification of UHMWPE/PU composite membrane

Z. G. Tang*, S. H. Teoh, W. McFarlane, L. A. Poole-Warren, M. Umezu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


Polyurethane composite made from biaxially drawn ultrahigh molecular weight polyethylene (BDUHMWPE) is likely an alternative for polyurethane currently being plagued for medical applications. In this study, an in vitro calcification protocol was used to determine the relative resistance to calcification of the composite membranes. The results demonstrated that the composite membranes were susceptible to extrinsic calcification that was closely related to the matrix polyurethane material used. The calcification of the composite was different from that of the solution cast polyurethane membranes. The incorporation of hydrophobic reinforcement BDUHMWPE effectively postponed the calcification. The differences of calcification between composite and polyurethane were greatly due to the differences in surface structures and properties of the as-cast polyurethane.

Original languageEnglish
Pages (from-to)149-152
Number of pages4
JournalMaterials Science and Engineering C
Issue number1-2
Publication statusPublished - 2002 May 31


  • Biaxially drawn ultrahigh molecular weight polyethylene
  • Composite
  • In vitro calcification
  • Polyether polyurethane

ASJC Scopus subject areas

  • General Materials Science
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering


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