Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt: Computational analysis of patient-specific virtual procedures

Jinlong Liu; Qi Sun; Mitsuo Umezu; Yi Qian; Haifa Hong; Zhou Du; Qian Wang; Yanjun Sun; Jinfen Liu

doi:10.1007/978-3-662-45283-7_7

Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt: Computational analysis of patient-specific virtual procedures

Jinlong Liu^*, Qi Sun, Mitsuo Umezu, Yi Qian, Haifa Hong, Zhou Du, Qian Wang, Yanjun Sun, Jinfen Liu

^*Corresponding author for this work

School of Creative Science and Engineering

Research output: Chapter in Book/Report/Conference proceeding › Chapter

8 Citations (Scopus)

Abstract

Currently, the modified Blalock-Taussig (mB-T) shunt is the most preferred surgery served as the first step of the staged procedures in the treatment of cyanotic congenital heart defect. A Gore-Tex conduit is used to surgically connect the systemic and pulmonary circulations. In the present study, we report on three-dimensional (3D) hemodynamic analysis of the effects of conduit anastomosis angles on hemodynamics of the mB-T shunt. We constructed a patient-specific 3D model after the mB-T shunt based on medical images and employed computer-aided design to reconstruct two new models with different anastomosis angles. The local pressure, blood flow distribution and wall shear stress were calculated. The results suggest the scheme of vertical anastomosis angle of the conduit on the pulmonary artery can increase the blood flow distribution from systemic circulation to two lungs and blood flows more smoothly in the conduit. The results are well congruent with our clinical experience. This indicates the numerical methods may be applied to investigate hemodynamics of the mB-T shunt for different surgical schemes.

Original language	English
Title of host publication	Life System Modeling and Simulation - International Conference on Life System Modeling and Simulation, LSMS 2014 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2014, Proceedings
Editors	Shiwei Ma, Li Jia, Xin Li, Ling Wang, Xin Sun, Huiyu Zhou
Publisher	Springer Verlag
Pages	62-71
Number of pages	10
ISBN (Electronic)	9783662452820
DOIs	https://doi.org/10.1007/978-3-662-45283-7_7
Publication status	Published - 2014

Publication series

Name	Communications in Computer and Information Science
Volume	461
ISSN (Print)	1865-0929
ISSN (Electronic)	1865-0937

Keywords

Computational fluid dynamics
Computer-aided Design
Congenital heart defect
Hemodynamics
Modified Blalock-Taussig shunt

ASJC Scopus subject areas

Computer Science(all)
Mathematics(all)

Access to Document

10.1007/978-3-662-45283-7_7

Cite this

Liu, J., Sun, Q., Umezu, M., Qian, Y., Hong, H., Du, Z., Wang, Q., Sun, Y., & Liu, J. (2014). Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt: Computational analysis of patient-specific virtual procedures. In S. Ma, L. Jia, X. Li, L. Wang, X. Sun, & H. Zhou (Eds.), Life System Modeling and Simulation - International Conference on Life System Modeling and Simulation, LSMS 2014 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2014, Proceedings (pp. 62-71). (Communications in Computer and Information Science; Vol. 461). Springer Verlag. https://doi.org/10.1007/978-3-662-45283-7_7

Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt: Computational analysis of patient-specific virtual procedures. / Liu, Jinlong; Sun, Qi; Umezu, Mitsuo et al.
Life System Modeling and Simulation - International Conference on Life System Modeling and Simulation, LSMS 2014 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2014, Proceedings. ed. / Shiwei Ma; Li Jia; Xin Li; Ling Wang; Xin Sun; Huiyu Zhou. Springer Verlag, 2014. p. 62-71 (Communications in Computer and Information Science; Vol. 461).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Liu, J, Sun, Q, Umezu, M, Qian, Y, Hong, H, Du, Z, Wang, Q, Sun, Y & Liu, J 2014, Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt: Computational analysis of patient-specific virtual procedures. in S Ma, L Jia, X Li, L Wang, X Sun & H Zhou (eds), Life System Modeling and Simulation - International Conference on Life System Modeling and Simulation, LSMS 2014 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2014, Proceedings. Communications in Computer and Information Science, vol. 461, Springer Verlag, pp. 62-71. https://doi.org/10.1007/978-3-662-45283-7_7

Liu J, Sun Q, Umezu M, Qian Y, Hong H, Du Z et al. Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt: Computational analysis of patient-specific virtual procedures. In Ma S, Jia L, Li X, Wang L, Sun X, Zhou H, editors, Life System Modeling and Simulation - International Conference on Life System Modeling and Simulation, LSMS 2014 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2014, Proceedings. Springer Verlag. 2014. p. 62-71. (Communications in Computer and Information Science). doi: 10.1007/978-3-662-45283-7_7

Liu, Jinlong ; Sun, Qi ; Umezu, Mitsuo et al. / Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt : Computational analysis of patient-specific virtual procedures. Life System Modeling and Simulation - International Conference on Life System Modeling and Simulation, LSMS 2014 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2014, Proceedings. editor / Shiwei Ma ; Li Jia ; Xin Li ; Ling Wang ; Xin Sun ; Huiyu Zhou. Springer Verlag, 2014. pp. 62-71 (Communications in Computer and Information Science).

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abstract = "Currently, the modified Blalock-Taussig (mB-T) shunt is the most preferred surgery served as the first step of the staged procedures in the treatment of cyanotic congenital heart defect. A Gore-Tex conduit is used to surgically connect the systemic and pulmonary circulations. In the present study, we report on three-dimensional (3D) hemodynamic analysis of the effects of conduit anastomosis angles on hemodynamics of the mB-T shunt. We constructed a patient-specific 3D model after the mB-T shunt based on medical images and employed computer-aided design to reconstruct two new models with different anastomosis angles. The local pressure, blood flow distribution and wall shear stress were calculated. The results suggest the scheme of vertical anastomosis angle of the conduit on the pulmonary artery can increase the blood flow distribution from systemic circulation to two lungs and blood flows more smoothly in the conduit. The results are well congruent with our clinical experience. This indicates the numerical methods may be applied to investigate hemodynamics of the mB-T shunt for different surgical schemes.",

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N2 - Currently, the modified Blalock-Taussig (mB-T) shunt is the most preferred surgery served as the first step of the staged procedures in the treatment of cyanotic congenital heart defect. A Gore-Tex conduit is used to surgically connect the systemic and pulmonary circulations. In the present study, we report on three-dimensional (3D) hemodynamic analysis of the effects of conduit anastomosis angles on hemodynamics of the mB-T shunt. We constructed a patient-specific 3D model after the mB-T shunt based on medical images and employed computer-aided design to reconstruct two new models with different anastomosis angles. The local pressure, blood flow distribution and wall shear stress were calculated. The results suggest the scheme of vertical anastomosis angle of the conduit on the pulmonary artery can increase the blood flow distribution from systemic circulation to two lungs and blood flows more smoothly in the conduit. The results are well congruent with our clinical experience. This indicates the numerical methods may be applied to investigate hemodynamics of the mB-T shunt for different surgical schemes.

AB - Currently, the modified Blalock-Taussig (mB-T) shunt is the most preferred surgery served as the first step of the staged procedures in the treatment of cyanotic congenital heart defect. A Gore-Tex conduit is used to surgically connect the systemic and pulmonary circulations. In the present study, we report on three-dimensional (3D) hemodynamic analysis of the effects of conduit anastomosis angles on hemodynamics of the mB-T shunt. We constructed a patient-specific 3D model after the mB-T shunt based on medical images and employed computer-aided design to reconstruct two new models with different anastomosis angles. The local pressure, blood flow distribution and wall shear stress were calculated. The results suggest the scheme of vertical anastomosis angle of the conduit on the pulmonary artery can increase the blood flow distribution from systemic circulation to two lungs and blood flows more smoothly in the conduit. The results are well congruent with our clinical experience. This indicates the numerical methods may be applied to investigate hemodynamics of the mB-T shunt for different surgical schemes.

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Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt: Computational analysis of patient-specific virtual procedures

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