TY - JOUR
T1 - Integrated profiling methods for identifying the targets of bioactive compounds
T2 - MorphoBase and ChemProteoBase
AU - Muroi, Makoto
AU - Futamura, Yushi
AU - Osada, Hiroyuki
N1 - Publisher Copyright:
© 2016 The Royal Society of Chemistry.
PY - 2016/5
Y1 - 2016/5
N2 - Covering: up to the end of 2015. Many useful compounds from natural products have been discovered through phenotype-based screening. However, the target identification process for compounds is laborious and time-consuming. With the development of new equipment and methodologies for biological analyses, a variety of profiling methods that utilize large sets of experimental data have been established. Here, we highlight the utility of our identification approaches, MorphoBase and ChemProteoBase.
AB - Covering: up to the end of 2015. Many useful compounds from natural products have been discovered through phenotype-based screening. However, the target identification process for compounds is laborious and time-consuming. With the development of new equipment and methodologies for biological analyses, a variety of profiling methods that utilize large sets of experimental data have been established. Here, we highlight the utility of our identification approaches, MorphoBase and ChemProteoBase.
UR - http://www.scopus.com/inward/record.url?scp=84973454483&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84973454483&partnerID=8YFLogxK
U2 - 10.1039/c5np00106d
DO - 10.1039/c5np00106d
M3 - Review article
C2 - 26996806
AN - SCOPUS:84973454483
SN - 0265-0568
VL - 33
SP - 621
EP - 625
JO - Natural Product Reports
JF - Natural Product Reports
IS - 5
ER -