Intensification of reactive distillation for TAME synthesis based on the analysis of multiple steady-state conditions

Takehiro Yamaki*, Keigo Matsuda, Duangkamol Na-Ranong, Hideyuki Matsumoto

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Our previous study reported that operation in multiple steady states contributes to an improvement in reaction conversion, making it possible to reduce the energy consumption of the reactive distillation process for tert-amyl methyl ether (TAME) synthesis. This study clarified the factors responsible for an improvement in the reaction conversion for operation in the multiple steady states of the reactive distillation column used in TAME synthesis. The column profiles for those conditions, in which multiple steady states existed and those in which they did not exist, were compared. The vapor and liquid flow rates with the multiple steady states were larger than those when the multiple steady states did not exist. The effect of the duty of the intermediate condenser, which was introduced at the top of the reactive section, on the liquid flow rate for a reflux ratio of 1 was examined. The amount of TAME production increased from 55.2 to 72.1 kmol/h when the intermediate condenser was operated at 0 to -5 MW. Furthermore, the effect of the intermediate reboiler duty on the reaction performance was evaluated. The results revealed that the liquid and vapor flow rates influenced the reaction and separation performances, respectively.

Original languageEnglish
Article number241
Issue number12
Publication statusPublished - 2018 Dec 1
Externally publishedYes


  • Multiple steady state
  • Reaction conversion
  • Reactive distillation
  • Steady state simulation
  • TAME synthesis

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering (miscellaneous)
  • Process Chemistry and Technology


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