Intracellular transport route of albumin in cultured aortic endothelial cells

Kenji Ikezawa*, Kazuki Ueno, Mariko Ikeda, Kotaro Oka, Kazuo Tanishita

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


Effects of colchicine on intracellular albumin transport in aortic endothelial cells have been shown as a reduction of the endocytic activity (Liu et al., 1993) and albumin transcytosis (Antohe et al., 1993). Since microtubules are possibly involved in the movement of vesicles, it is important to understand that microtubules are associated with albumin transport within cells. In our in vitro study, the organization of endocytic compartments were analyzed after internalization of fluorescent-labeled albumin in cultured porcine aortic endothelial cells. We found that microtubules were not only involved in a later step but also early step of endocytosis (containing internalization).

Original languageEnglish
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Number of pages2
Publication statusPublished - 1998
Externally publishedYes

ASJC Scopus subject areas

  • Engineering(all)


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