Investigation of a hydrodynamic performance of a ventricular assist device after its long-term use in clinical application

Yuma Kokuzawa; Tomohiro Shima; Masateru Furusato; Kazuhiko Ito; Takashi Tanaka; Toshihiro Igarashi; Tomohiro Nishinaka; Kiyotaka Iwasaki; Mitsuo Umezu

doi:10.1007/978-3-540-74771-0_49

Investigation of a hydrodynamic performance of a ventricular assist device after its long-term use in clinical application

Yuma Kokuzawa^*, Tomohiro Shima, Masateru Furusato, Kazuhiko Ito, Takashi Tanaka, Toshihiro Igarashi, Tomohiro Nishinaka, Kiyotaka Iwasaki, Mitsuo Umezu

^*Corresponding author for this work

Graduate School of Advanced Science and Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

A long-term durability of a ventricular assist device (VAD) is required due to a shortage of donor hearts for cardiac transplantation, but there is no analyzed pump data after long-term use. This study aimed to perform a comparative study between new VAD and VADs after long-term use. The hydrodynamic performance of the used Toyobo VADs (mean period of 5 months with the maximum of 12 months) was evaluated in a mock circulatory system, where a new VAD was used as a control. Although a remarkable difference was not observed in terms of mean flow rate, flow and pressure waveforms varied significantly. Then, the pressure-volume relationship of each pump was measured. It was found that the capacity of long-term VADs was reduced. Although a further study is required, these results suggested that a long-term use of VAD may cause a change in mechanical properties of polymer materials.

Original language	English
Title of host publication	Life System Modeling and Simulation - International Conference, LSMS 2007, Proceedings
Publisher	Springer Verlag
Pages	429-435
Number of pages	7
ISBN (Print)	9783540747703
DOIs	https://doi.org/10.1007/978-3-540-74771-0_49
Publication status	Published - 2007
Event	2007 International Conference on Life System Modeling and Simulation, LSMS 2007 - Shanghai, China Duration: 2007 Sept 14 → 2007 Sept 17

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume	4689 LNBI
ISSN (Print)	0302-9743
ISSN (Electronic)	1611-3349

Conference

Conference	2007 International Conference on Life System Modeling and Simulation, LSMS 2007
Country/Territory	China
City	Shanghai
Period	07/9/14 → 07/9/17

ASJC Scopus subject areas

Theoretical Computer Science
Computer Science(all)

Access to Document

10.1007/978-3-540-74771-0_49

Cite this

Kokuzawa, Y., Shima, T., Furusato, M., Ito, K., Tanaka, T., Igarashi, T., Nishinaka, T., Iwasaki, K., & Umezu, M. (2007). Investigation of a hydrodynamic performance of a ventricular assist device after its long-term use in clinical application. In Life System Modeling and Simulation - International Conference, LSMS 2007, Proceedings (pp. 429-435). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 4689 LNBI). Springer Verlag. https://doi.org/10.1007/978-3-540-74771-0_49

Investigation of a hydrodynamic performance of a ventricular assist device after its long-term use in clinical application. / Kokuzawa, Yuma; Shima, Tomohiro; Furusato, Masateru et al.
Life System Modeling and Simulation - International Conference, LSMS 2007, Proceedings. Springer Verlag, 2007. p. 429-435 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 4689 LNBI).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Kokuzawa, Y, Shima, T, Furusato, M, Ito, K, Tanaka, T, Igarashi, T, Nishinaka, T, Iwasaki, K & Umezu, M 2007, Investigation of a hydrodynamic performance of a ventricular assist device after its long-term use in clinical application. in Life System Modeling and Simulation - International Conference, LSMS 2007, Proceedings. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 4689 LNBI, Springer Verlag, pp. 429-435, 2007 International Conference on Life System Modeling and Simulation, LSMS 2007, Shanghai, China, 07/9/14. https://doi.org/10.1007/978-3-540-74771-0_49

Kokuzawa Y, Shima T, Furusato M, Ito K, Tanaka T, Igarashi T et al. Investigation of a hydrodynamic performance of a ventricular assist device after its long-term use in clinical application. In Life System Modeling and Simulation - International Conference, LSMS 2007, Proceedings. Springer Verlag. 2007. p. 429-435. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)). doi: 10.1007/978-3-540-74771-0_49

Kokuzawa, Yuma ; Shima, Tomohiro ; Furusato, Masateru et al. / Investigation of a hydrodynamic performance of a ventricular assist device after its long-term use in clinical application. Life System Modeling and Simulation - International Conference, LSMS 2007, Proceedings. Springer Verlag, 2007. pp. 429-435 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).

@inproceedings{f0da33d848e74f00b7a17110e1ec7d53,

title = "Investigation of a hydrodynamic performance of a ventricular assist device after its long-term use in clinical application",

abstract = "A long-term durability of a ventricular assist device (VAD) is required due to a shortage of donor hearts for cardiac transplantation, but there is no analyzed pump data after long-term use. This study aimed to perform a comparative study between new VAD and VADs after long-term use. The hydrodynamic performance of the used Toyobo VADs (mean period of 5 months with the maximum of 12 months) was evaluated in a mock circulatory system, where a new VAD was used as a control. Although a remarkable difference was not observed in terms of mean flow rate, flow and pressure waveforms varied significantly. Then, the pressure-volume relationship of each pump was measured. It was found that the capacity of long-term VADs was reduced. Although a further study is required, these results suggested that a long-term use of VAD may cause a change in mechanical properties of polymer materials.",

author = "Yuma Kokuzawa and Tomohiro Shima and Masateru Furusato and Kazuhiko Ito and Takashi Tanaka and Toshihiro Igarashi and Tomohiro Nishinaka and Kiyotaka Iwasaki and Mitsuo Umezu",

year = "2007",

doi = "10.1007/978-3-540-74771-0_49",

language = "English",

isbn = "9783540747703",

series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",

publisher = "Springer Verlag",

pages = "429--435",

booktitle = "Life System Modeling and Simulation - International Conference, LSMS 2007, Proceedings",

note = "2007 International Conference on Life System Modeling and Simulation, LSMS 2007 ; Conference date: 14-09-2007 Through 17-09-2007",

}

TY - GEN

T1 - Investigation of a hydrodynamic performance of a ventricular assist device after its long-term use in clinical application

AU - Kokuzawa, Yuma

AU - Shima, Tomohiro

AU - Furusato, Masateru

AU - Ito, Kazuhiko

AU - Tanaka, Takashi

AU - Igarashi, Toshihiro

AU - Nishinaka, Tomohiro

AU - Iwasaki, Kiyotaka

AU - Umezu, Mitsuo

PY - 2007

Y1 - 2007

N2 - A long-term durability of a ventricular assist device (VAD) is required due to a shortage of donor hearts for cardiac transplantation, but there is no analyzed pump data after long-term use. This study aimed to perform a comparative study between new VAD and VADs after long-term use. The hydrodynamic performance of the used Toyobo VADs (mean period of 5 months with the maximum of 12 months) was evaluated in a mock circulatory system, where a new VAD was used as a control. Although a remarkable difference was not observed in terms of mean flow rate, flow and pressure waveforms varied significantly. Then, the pressure-volume relationship of each pump was measured. It was found that the capacity of long-term VADs was reduced. Although a further study is required, these results suggested that a long-term use of VAD may cause a change in mechanical properties of polymer materials.

AB - A long-term durability of a ventricular assist device (VAD) is required due to a shortage of donor hearts for cardiac transplantation, but there is no analyzed pump data after long-term use. This study aimed to perform a comparative study between new VAD and VADs after long-term use. The hydrodynamic performance of the used Toyobo VADs (mean period of 5 months with the maximum of 12 months) was evaluated in a mock circulatory system, where a new VAD was used as a control. Although a remarkable difference was not observed in terms of mean flow rate, flow and pressure waveforms varied significantly. Then, the pressure-volume relationship of each pump was measured. It was found that the capacity of long-term VADs was reduced. Although a further study is required, these results suggested that a long-term use of VAD may cause a change in mechanical properties of polymer materials.

UR - http://www.scopus.com/inward/record.url?scp=38049153438&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38049153438&partnerID=8YFLogxK

U2 - 10.1007/978-3-540-74771-0_49

DO - 10.1007/978-3-540-74771-0_49

M3 - Conference contribution

AN - SCOPUS:38049153438

SN - 9783540747703

T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

SP - 429

EP - 435

BT - Life System Modeling and Simulation - International Conference, LSMS 2007, Proceedings

PB - Springer Verlag

T2 - 2007 International Conference on Life System Modeling and Simulation, LSMS 2007

Y2 - 14 September 2007 through 17 September 2007

ER -

Investigation of a hydrodynamic performance of a ventricular assist device after its long-term use in clinical application

Abstract

Publication series

Conference

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this