Abstract
The first catalytic and enantioselective C-H alkylation of ferrocene derivatives with various alkenes was achieved. A cationic iridium complex, having a chiral diene ligand, and an isoquinolyl moiety as a directing group are essential for regioselective and enantioselective C-H bond activation. Director's cut: The first catalytic and enantioselective C-H alkylation of ferrocene derivatives with various alkenes was achieved. A cationic iridium complex, having a chiral diene ligand, and an isoquinolyl moiety as a directing group are essential for regioselective and enantioselective C-H bond activation. coe=cyclooctene, NaBARF=sodium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate.
| Original language | English |
|---|---|
| Pages (from-to) | 5410-5413 |
| Number of pages | 4 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 53 |
| Issue number | 21 |
| DOIs | |
| Publication status | Published - 2014 May 19 |
Keywords
- C-H activation
- alkylation
- enantioselectivity
- iridium
- synthetic methods
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)