TY - GEN
T1 - Manufacture of cell fusion device utilizing mechanical fabrication and FIB fabrication
AU - Umezu, S.
AU - Naruse, T.
AU - Gong, J. S.
AU - Ohmori, H.
AU - Ito, Y.
AU - Katahira, K.
PY - 2009
Y1 - 2009
N2 - We manufactured preliminary cell fusion device utilizing mechanical fabrication and FIB (Focused-Ion Beam) fabrication instead of PDMS (Polydimethylsiloxane) stamp fabrication. In general, bio devices are made in several days utilizing the PDMS stamp fabrication. The purpose of this study is to manufacture micro bio device precisely and rapidly. In this paper, we tried to apply mechanical fabrication and FIB fabrication for making a cell fusion device. We made micro channels utilizing the mechanical fabrication. The material of the device in this case was acryl. Because acryl was elastic in room temperature, it was difficult to make a device precisely by mechanical fabrication in room temperature. So, the channels were made in cooling condition. The depth and the width of the channels were about 50 μm. After the process of mechanical fabrication was completed, the process of FIB fabrication was carried out to make the part of cell fusion. This combined fabrication method has good merits. Those are rapid and easy fabrication and possibility of re-fabrication. The latter merit is positive for ecology because error devices have possibility of availability instead of waste.
AB - We manufactured preliminary cell fusion device utilizing mechanical fabrication and FIB (Focused-Ion Beam) fabrication instead of PDMS (Polydimethylsiloxane) stamp fabrication. In general, bio devices are made in several days utilizing the PDMS stamp fabrication. The purpose of this study is to manufacture micro bio device precisely and rapidly. In this paper, we tried to apply mechanical fabrication and FIB fabrication for making a cell fusion device. We made micro channels utilizing the mechanical fabrication. The material of the device in this case was acryl. Because acryl was elastic in room temperature, it was difficult to make a device precisely by mechanical fabrication in room temperature. So, the channels were made in cooling condition. The depth and the width of the channels were about 50 μm. After the process of mechanical fabrication was completed, the process of FIB fabrication was carried out to make the part of cell fusion. This combined fabrication method has good merits. Those are rapid and easy fabrication and possibility of re-fabrication. The latter merit is positive for ecology because error devices have possibility of availability instead of waste.
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M3 - Conference contribution
AN - SCOPUS:84908294386
T3 - Proceedings of the 9th International Conference of the European Society for Precision Engineering and Nanotechnology, EUSPEN 2009
SP - 297
EP - 300
BT - Proceedings of the 9th International Conference of the European Society for Precision Engineering and Nanotechnology, EUSPEN 2009
A2 - Brinksmeier, E.
A2 - Burke, Theresa
A2 - Van Brussel, Hendrik
A2 - Spaan, H.
PB - euspen
T2 - 9th International Conference of the European Society for Precision Engineering and Nanotechnology, EUSPEN 2009
Y2 - 2 June 2009 through 5 June 2009
ER -