Medical image-based analysis of flow in heart with congenital heart disease: Numerical simulation of intraventricular flow

Lijun Chen; Jinlong Liu; Haifa Hong; Aimin Sun; Jinfen Liu; Yuqi Zhang; Mitsuo Umezu

doi:10.1109/ASCC.2015.7244764

Medical image-based analysis of flow in heart with congenital heart disease: Numerical simulation of intraventricular flow

Lijun Chen, Jinlong Liu, Haifa Hong, Aimin Sun, Jinfen Liu, Yuqi Zhang^*, Mitsuo Umezu

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

Quantitatively analyze the characteristics of intraventricular flow is critical for the diagnosis of congenital heart disease (CHD). Although several techniques are applied in clinic currently, the information which they provided is not satisfied with the requirement of the therapies of CHD. Here, we introduced the method of computational fluid dynamics (CFD) to investigate the intraventricular hemodynamics using a reconstructed model of left ventricle (LV) based on cardiac magnetic resonance (CMR) images. A large, counterclockwise, vortex was observed. It persisted in the periods of slow filling phase and atrial contraction phase in diastole. A smaller vortex was found around the outflow tract. An annular vortex is formed in the base region downstream of the mitral orifice. The vortices vanished quickly at the end-diastole. These results indicate the technique of CFD is a promising tool which can be used to evaluate the hemodynamics in LV. Understanding the characteristics of intraventricular flow is helpful for the improvement of CHD.

Original language	English
Title of host publication	2015 10th Asian Control Conference: Emerging Control Techniques for a Sustainable World, ASCC 2015
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Print)	9781479978625
DOIs	https://doi.org/10.1109/ASCC.2015.7244764
Publication status	Published - 2015 Sept 8
Event	10th Asian Control Conference, ASCC 2015 - Kota Kinabalu, Malaysia Duration: 2015 May 31 → 2015 Jun 3

Other

Other	10th Asian Control Conference, ASCC 2015
Country/Territory	Malaysia
City	Kota Kinabalu
Period	15/5/31 → 15/6/3

Keywords

computational fluid dynamics
congenital heart disease
hemodynamics
intraventricular flow
left ventricle

ASJC Scopus subject areas

Control and Systems Engineering

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10.1109/ASCC.2015.7244764

Cite this

Chen, L., Liu, J., Hong, H., Sun, A., Liu, J., Zhang, Y., & Umezu, M. (2015). Medical image-based analysis of flow in heart with congenital heart disease: Numerical simulation of intraventricular flow. In 2015 10th Asian Control Conference: Emerging Control Techniques for a Sustainable World, ASCC 2015 Article 7244764 Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ASCC.2015.7244764

Medical image-based analysis of flow in heart with congenital heart disease: Numerical simulation of intraventricular flow. / Chen, Lijun; Liu, Jinlong; Hong, Haifa et al.
2015 10th Asian Control Conference: Emerging Control Techniques for a Sustainable World, ASCC 2015. Institute of Electrical and Electronics Engineers Inc., 2015. 7244764.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Chen, L, Liu, J, Hong, H, Sun, A, Liu, J, Zhang, Y & Umezu, M 2015, Medical image-based analysis of flow in heart with congenital heart disease: Numerical simulation of intraventricular flow. in 2015 10th Asian Control Conference: Emerging Control Techniques for a Sustainable World, ASCC 2015., 7244764, Institute of Electrical and Electronics Engineers Inc., 10th Asian Control Conference, ASCC 2015, Kota Kinabalu, Malaysia, 15/5/31. https://doi.org/10.1109/ASCC.2015.7244764

Chen L, Liu J, Hong H, Sun A, Liu J, Zhang Y et al. Medical image-based analysis of flow in heart with congenital heart disease: Numerical simulation of intraventricular flow. In 2015 10th Asian Control Conference: Emerging Control Techniques for a Sustainable World, ASCC 2015. Institute of Electrical and Electronics Engineers Inc. 2015. 7244764 doi: 10.1109/ASCC.2015.7244764

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abstract = "Quantitatively analyze the characteristics of intraventricular flow is critical for the diagnosis of congenital heart disease (CHD). Although several techniques are applied in clinic currently, the information which they provided is not satisfied with the requirement of the therapies of CHD. Here, we introduced the method of computational fluid dynamics (CFD) to investigate the intraventricular hemodynamics using a reconstructed model of left ventricle (LV) based on cardiac magnetic resonance (CMR) images. A large, counterclockwise, vortex was observed. It persisted in the periods of slow filling phase and atrial contraction phase in diastole. A smaller vortex was found around the outflow tract. An annular vortex is formed in the base region downstream of the mitral orifice. The vortices vanished quickly at the end-diastole. These results indicate the technique of CFD is a promising tool which can be used to evaluate the hemodynamics in LV. Understanding the characteristics of intraventricular flow is helpful for the improvement of CHD.",

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AB - Quantitatively analyze the characteristics of intraventricular flow is critical for the diagnosis of congenital heart disease (CHD). Although several techniques are applied in clinic currently, the information which they provided is not satisfied with the requirement of the therapies of CHD. Here, we introduced the method of computational fluid dynamics (CFD) to investigate the intraventricular hemodynamics using a reconstructed model of left ventricle (LV) based on cardiac magnetic resonance (CMR) images. A large, counterclockwise, vortex was observed. It persisted in the periods of slow filling phase and atrial contraction phase in diastole. A smaller vortex was found around the outflow tract. An annular vortex is formed in the base region downstream of the mitral orifice. The vortices vanished quickly at the end-diastole. These results indicate the technique of CFD is a promising tool which can be used to evaluate the hemodynamics in LV. Understanding the characteristics of intraventricular flow is helpful for the improvement of CHD.

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Medical image-based analysis of flow in heart with congenital heart disease: Numerical simulation of intraventricular flow

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