TY - GEN
T1 - Micro-scale droplet contact method by mechanical motion
T2 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
AU - Zaleha, L. N S
AU - Kawano, R.
AU - Yasuga, Hiroki
AU - Kamiya, K.
AU - Osaki, T.
AU - Miki, N.
AU - Takeuchi, S.
PY - 2013/1/1
Y1 - 2013/1/1
N2 - We prepare a micro-scale droplet contact method by mechanical motion which applying the Split-and-Contact Device (SCD) theory. The interval distance of well opening is designed for limiting the surface area of interface of water droplets. When the droplets are split and joined together, the lipid monolayer surrounding them at the interval combine to form a robust lipid bilayer. The α-hemolysin that acts as pores, incorporate into the lipid bilayer and allows the ionic currents to be flow across lipid bilayer and measured. We present three different interval distance of well opening.
AB - We prepare a micro-scale droplet contact method by mechanical motion which applying the Split-and-Contact Device (SCD) theory. The interval distance of well opening is designed for limiting the surface area of interface of water droplets. When the droplets are split and joined together, the lipid monolayer surrounding them at the interval combine to form a robust lipid bilayer. The α-hemolysin that acts as pores, incorporate into the lipid bilayer and allows the ionic currents to be flow across lipid bilayer and measured. We present three different interval distance of well opening.
KW - Bilayer lipid membrane (BLM)
KW - Micro-scale droplet
KW - Split-and-Contact Device (SCD)
UR - http://www.scopus.com/inward/record.url?scp=84907340599&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84907340599&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84907340599
SN - 9781632666246
T3 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
SP - 1433
EP - 1435
BT - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PB - Chemical and Biological Microsystems Society
Y2 - 27 October 2013 through 31 October 2013
ER -