Microfluidic sedimentation system for separation of plasma from whole blood

Chiaki Kuroda; Yoshimichi Ohki; Hiroki Ashiba; Makoto Fujimaki; Koichi Awazu; Torahiko Tanaka; Makoto Makishima

doi:10.1109/ICSENS.2014.6985389

Microfluidic sedimentation system for separation of plasma from whole blood

Chiaki Kuroda, Yoshimichi Ohki, Hiroki Ashiba, Makoto Fujimaki, Koichi Awazu^*, Torahiko Tanaka, Makoto Makishima

^*Corresponding author for this work

Kagami Memorial Research Institute for Materials Science and Technology

Research output: Contribution to journal › Conference article › peer-review

7 Citations (Scopus)

Abstract

A microfluidic system for a portable and speedy blood test device has been developed. In the system, blood is injected into a cylindrical channel with a diameter of 3.0 mm and a height of 3.0 mm from the bottom to the top. When the blood ascends the channel, blood cells sediment at the bottom and plasma is separated at the top. This system can be manufactured easily at a low cost by simply bonding two identical polydimethylsiloxane chips. Pure plasma can be obtained successfully from a very tiny amount of blood, less than a drop (9 μL).

Original language	English
Article number	6985389
Pages (from-to)	1854-1857
Number of pages	4
Journal	Proceedings of IEEE Sensors
Volume	2014-December
Issue number	December
DOIs	https://doi.org/10.1109/ICSENS.2014.6985389
Publication status	Published - 2014 Dec 12
Event	13th IEEE SENSORS Conference, SENSORS 2014 - Valencia, Spain Duration: 2014 Nov 2 → 2014 Nov 5

Keywords

Blood
Microfluidics
Plasma extraction
Sedimentation

ASJC Scopus subject areas

Electrical and Electronic Engineering

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10.1109/ICSENS.2014.6985389

Cite this

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abstract = "A microfluidic system for a portable and speedy blood test device has been developed. In the system, blood is injected into a cylindrical channel with a diameter of 3.0 mm and a height of 3.0 mm from the bottom to the top. When the blood ascends the channel, blood cells sediment at the bottom and plasma is separated at the top. This system can be manufactured easily at a low cost by simply bonding two identical polydimethylsiloxane chips. Pure plasma can be obtained successfully from a very tiny amount of blood, less than a drop (9 μL).",

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AU - Kuroda, Chiaki

AU - Ohki, Yoshimichi

AU - Ashiba, Hiroki

AU - Fujimaki, Makoto

AU - Awazu, Koichi

AU - Tanaka, Torahiko

AU - Makishima, Makoto

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N2 - A microfluidic system for a portable and speedy blood test device has been developed. In the system, blood is injected into a cylindrical channel with a diameter of 3.0 mm and a height of 3.0 mm from the bottom to the top. When the blood ascends the channel, blood cells sediment at the bottom and plasma is separated at the top. This system can be manufactured easily at a low cost by simply bonding two identical polydimethylsiloxane chips. Pure plasma can be obtained successfully from a very tiny amount of blood, less than a drop (9 μL).

AB - A microfluidic system for a portable and speedy blood test device has been developed. In the system, blood is injected into a cylindrical channel with a diameter of 3.0 mm and a height of 3.0 mm from the bottom to the top. When the blood ascends the channel, blood cells sediment at the bottom and plasma is separated at the top. This system can be manufactured easily at a low cost by simply bonding two identical polydimethylsiloxane chips. Pure plasma can be obtained successfully from a very tiny amount of blood, less than a drop (9 μL).

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KW - Microfluidics

KW - Plasma extraction

KW - Sedimentation

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Microfluidic sedimentation system for separation of plasma from whole blood

Abstract

Keywords

ASJC Scopus subject areas

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