TY - JOUR
T1 - Mumiamicin
T2 - Structure and bioactivity of a new furan fatty acid from Mumia sp. YSP-2-79
AU - Kimura, Tōru
AU - Tajima, Ayano
AU - Inahashi, Yuki
AU - Iwatsuki, Masato
AU - Kasai, Hiroaki
AU - Mokudai, Takayuki
AU - Niwano, Yoshimi
AU - Shiomi, Kazuro
AU - Takahashi, Yōko
AU - Ōmura, Satoshi
AU - Nakashima, Takuji
N1 - Funding Information:
This study was supported by funding from the Institute for Fermentation, Osaka (IFO), Japan.
Publisher Copyright:
© 2018 Applied Microbiology, Molecular and Cellular Biosciences Research Foundation.
PY - 2018
Y1 - 2018
N2 - A new antibiotic, designated mumiamicin, was isolated from the cultured broth of the rare actinomycete strain, Mumia sp. YSP-2-79, by Diaion HP-20, silica gel and ODS column chromatography, followed by HPLC purification. The chemical structure of mumiamicin was elucidated as a new furan fatty acid by nuclear magnetic resonance and mass spectrometry. Mumiamicin showed antimicrobial activity and antioxidative activity.
AB - A new antibiotic, designated mumiamicin, was isolated from the cultured broth of the rare actinomycete strain, Mumia sp. YSP-2-79, by Diaion HP-20, silica gel and ODS column chromatography, followed by HPLC purification. The chemical structure of mumiamicin was elucidated as a new furan fatty acid by nuclear magnetic resonance and mass spectrometry. Mumiamicin showed antimicrobial activity and antioxidative activity.
KW - Antioxidative activity
KW - Furan fatty acid
KW - Marine actinomycete
KW - Mumiamicin
KW - Physicochemical screening
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U2 - 10.2323/jgam.2017.06.004
DO - 10.2323/jgam.2017.06.004
M3 - Article
C2 - 29367492
AN - SCOPUS:85047254025
SN - 0022-1260
VL - 64
SP - 62
EP - 67
JO - Journal of General and Applied Microbiology
JF - Journal of General and Applied Microbiology
IS - 2
ER -
