Necrotizing fasciitis caused by Streptococcus pneumoniae in mixed connective tissue disease

Takamichi Yuhara*, Hiroyuki Takemura, Takao Akama, Kazuhide Yamane, Takayuki Sumida

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


A 42-year-old man was hospitalized because of chills, fever, and severe polyarthralgia. He had a 5-year history of mixed connective tissue disease (MCTD) with polyarthritis which had been treated with a nonsteroidal anti-inflammatory drug alone. On the second day of hospitalization, necrotizing fasciitis of the right leg developed. Streptococcus pneumoniae was later detected in a blood culture. Pneumococcal infections of the soft tissues are uncommon, and have been reported in immunosuppressed patients and patients with systemic lupus erythematosus. This is the first report of a case of necrotizing fasciitis caused by S. pneumoniae in a patient with MCTD.

Original languageEnglish
Pages (from-to)180-182
Number of pages3
JournalModern Rheumatology
Issue number3
Publication statusPublished - 2000 Jan 9
Externally publishedYes


  • Mixed connective tissue disease
  • Necrotizing fasciitis
  • Streptococcus pneumoniae

ASJC Scopus subject areas

  • Rheumatology


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