Nickel-catalyzed alkenylation and alkylation of fluoroarenes via activation of C-H bond over C-F bond

Yoshiaki Nakao; Natsuko Kashihara; Kyalo Stephen Kanyiva; Tamejiro Hiyama

doi:10.1021/ja807258m

Nickel-catalyzed alkenylation and alkylation of fluoroarenes via activation of C-H bond over C-F bond

Yoshiaki Nakao^*, Natsuko Kashihara, Kyalo Stephen Kanyiva, Tamejiro Hiyama

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

212 Citations (Scopus)

Abstract

Nickel/P(c-C₅H₉)₃ (PCyp₃) catalyst effects the addition reactions of fluoroarenes across alkynes, 1,3-dienes, and vinylarenes via the activation of C-H bonds over C-F bonds. The acidic C-H bonds located ortho to fluorine are exclusively activated to afford a range of alkenylated and alkylated fluoroarenes.

Original language	English
Pages (from-to)	16170-16171
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	130
Issue number	48
DOIs	https://doi.org/10.1021/ja807258m
Publication status	Published - 2008 Dec 3
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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abstract = "Nickel/P(c-C5H9)3 (PCyp3) catalyst effects the addition reactions of fluoroarenes across alkynes, 1,3-dienes, and vinylarenes via the activation of C-H bonds over C-F bonds. The acidic C-H bonds located ortho to fluorine are exclusively activated to afford a range of alkenylated and alkylated fluoroarenes.",

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AU - Kanyiva, Kyalo Stephen

AU - Hiyama, Tamejiro

PY - 2008/12/3

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Nickel-catalyzed alkenylation and alkylation of fluoroarenes via activation of C-H bond over C-F bond

Abstract

ASJC Scopus subject areas

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