Noninvasive diagnostics supporting system for choroidal melanoma: a pilot study

Ori Kameyama; Yoshihiko Usui; Keisuke Kimura; Atsushi Nakamura; Takayuki Sota; Hiroshi Goto

doi:10.1007/s10384-014-0351-3

Noninvasive diagnostics supporting system for choroidal melanoma: a pilot study

Ori Kameyama, Yoshihiko Usui^*, Keisuke Kimura, Atsushi Nakamura, Takayuki Sota, Hiroshi Goto

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Purpose: To examine the usefulness of a near-infrared hyperspectral imager (NIR-HSI) system in discriminating uveal melanoma from other intraocular tumors. Method: The NIR-HSI, which had been developed as a screening system for age-related macular degeneration, was used to measure near-infrared hyperspectral data (NIR-HSD) of a lesion located at the ocular fundus of 17 Japanese patients, including 5 with choroidal melanoma and 12 with other intraocular tumors. The index was derived from each NIR-HSD. Non-parametric statistical analysis was performed. Results: Diagnostic accuracy of 94.1 % was achieved when the threshold value of the index was set to minimize the average value of false-positive and -negative fractions. Conclusions: The NIR-HSI system is useful as a noninvasive diagnostic supporting system for choroidal melanoma.

Original language	English
Pages (from-to)	48-54
Number of pages	7
Journal	Japanese Journal of Ophthalmology
Volume	59
Issue number	1
DOIs	https://doi.org/10.1007/s10384-014-0351-3
Publication status	Published - 2015 Jan

Keywords

Choroidal melanoma
Near-Infrared hyperspectral imager

ASJC Scopus subject areas

Ophthalmology

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10.1007/s10384-014-0351-3

Cite this

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title = "Noninvasive diagnostics supporting system for choroidal melanoma: a pilot study",

abstract = "Purpose: To examine the usefulness of a near-infrared hyperspectral imager (NIR-HSI) system in discriminating uveal melanoma from other intraocular tumors. Method: The NIR-HSI, which had been developed as a screening system for age-related macular degeneration, was used to measure near-infrared hyperspectral data (NIR-HSD) of a lesion located at the ocular fundus of 17 Japanese patients, including 5 with choroidal melanoma and 12 with other intraocular tumors. The index was derived from each NIR-HSD. Non-parametric statistical analysis was performed. Results: Diagnostic accuracy of 94.1 % was achieved when the threshold value of the index was set to minimize the average value of false-positive and -negative fractions. Conclusions: The NIR-HSI system is useful as a noninvasive diagnostic supporting system for choroidal melanoma.",

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T1 - Noninvasive diagnostics supporting system for choroidal melanoma

T2 - a pilot study

AU - Kameyama, Ori

AU - Usui, Yoshihiko

AU - Kimura, Keisuke

AU - Nakamura, Atsushi

AU - Sota, Takayuki

AU - Goto, Hiroshi

PY - 2015/1

Y1 - 2015/1

N2 - Purpose: To examine the usefulness of a near-infrared hyperspectral imager (NIR-HSI) system in discriminating uveal melanoma from other intraocular tumors. Method: The NIR-HSI, which had been developed as a screening system for age-related macular degeneration, was used to measure near-infrared hyperspectral data (NIR-HSD) of a lesion located at the ocular fundus of 17 Japanese patients, including 5 with choroidal melanoma and 12 with other intraocular tumors. The index was derived from each NIR-HSD. Non-parametric statistical analysis was performed. Results: Diagnostic accuracy of 94.1 % was achieved when the threshold value of the index was set to minimize the average value of false-positive and -negative fractions. Conclusions: The NIR-HSI system is useful as a noninvasive diagnostic supporting system for choroidal melanoma.

AB - Purpose: To examine the usefulness of a near-infrared hyperspectral imager (NIR-HSI) system in discriminating uveal melanoma from other intraocular tumors. Method: The NIR-HSI, which had been developed as a screening system for age-related macular degeneration, was used to measure near-infrared hyperspectral data (NIR-HSD) of a lesion located at the ocular fundus of 17 Japanese patients, including 5 with choroidal melanoma and 12 with other intraocular tumors. The index was derived from each NIR-HSD. Non-parametric statistical analysis was performed. Results: Diagnostic accuracy of 94.1 % was achieved when the threshold value of the index was set to minimize the average value of false-positive and -negative fractions. Conclusions: The NIR-HSI system is useful as a noninvasive diagnostic supporting system for choroidal melanoma.

KW - Choroidal melanoma

KW - Near-Infrared hyperspectral imager

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Noninvasive diagnostics supporting system for choroidal melanoma: a pilot study

Abstract

Keywords

ASJC Scopus subject areas

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