TY - GEN
T1 - Noninvasive measurement of physiological functions in a living body by transillumination
AU - Shimizu, Koichi
AU - Kitama, Masataka
AU - Mouri, Mitsuhiro
AU - Yamamoto, Katsuyuki
PY - 1994/1/1
Y1 - 1994/1/1
N2 - With the view toward the non-invasive imaging of biological functions with light, a fundamental study has been conducted. Using a near-infrared light, the transillumination images of the head of a rat were obtained. The change in the image was investigated, when the oxygen fraction of inhalation gas was changed and when the brain circulation was changed by occluding the carotid artery. It was found that the changes in the brain blood volume and in the brain oxygenation state can be detected using multiple wavelengths of light. Further, the spatial distribution of these changes can be visualized in the transillumination images of a brain. Through this study, the feasibility of optical trans-body imaging of physiological functions was verified.
AB - With the view toward the non-invasive imaging of biological functions with light, a fundamental study has been conducted. Using a near-infrared light, the transillumination images of the head of a rat were obtained. The change in the image was investigated, when the oxygen fraction of inhalation gas was changed and when the brain circulation was changed by occluding the carotid artery. It was found that the changes in the brain blood volume and in the brain oxygenation state can be detected using multiple wavelengths of light. Further, the spatial distribution of these changes can be visualized in the transillumination images of a brain. Through this study, the feasibility of optical trans-body imaging of physiological functions was verified.
UR - http://www.scopus.com/inward/record.url?scp=85064602655&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85064602655&partnerID=8YFLogxK
U2 - 10.1109/IMTC.1994.351941
DO - 10.1109/IMTC.1994.351941
M3 - Conference contribution
AN - SCOPUS:85064602655
T3 - Conference Proceedings - 10th Anniv., IMTC 1994: Advanced Technologies in I and M. 1994 IEEE Instrumentation and Measurement Technology Conference
SP - 982
EP - 985
BT - Conference Proceedings - 10th Anniv., IMTC 1994
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 1994 IEEE Instrumentation and Measurement Technology Conference, IMTC 1994
Y2 - 10 May 1994 through 12 May 1994
ER -