Numerical simulation of adhesion of cells in micro channels using the MPS method

Yukihito Suzuki; Masaki Koishikawa; Seiichi Koshizuka; Takuji Okamoto; Naotsugu Kaneko; Atsuko Takamatsu; Teruo Fujii

doi:10.1299/kikaib.72.2109

Numerical simulation of adhesion of cells in micro channels using the MPS method

Yukihito Suzuki^*, Masaki Koishikawa, Seiichi Koshizuka, Takuji Okamoto, Naotsugu Kaneko, Atsuko Takamatsu, Teruo Fujii

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The MPS method is a particle method which simulates motion of continua with a finite number of particles. Thus it is relatively easy to simulate complex flows such as those in a bioreactor in which the geometry of flow is continuously modified by adhesion of cells. In this study, flows with adhesion of cells in a micro channel are simulated using the MPS method. The adhesion pattern of cells is well reproduced by the simulation.

Original language	English
Pages (from-to)	2109-2116
Number of pages	8
Journal	Nihon Kikai Gakkai Ronbunshu, B Hen/Transactions of the Japan Society of Mechanical Engineers, Part B
Volume	72
Issue number	9
DOIs	https://doi.org/10.1299/kikaib.72.2109
Publication status	Published - 2006 Sept
Externally published	Yes

Keywords

Bio-fluid mechanics
Computational fluid dynamics
Micro flow
Particle method
Viscous flow

ASJC Scopus subject areas

Condensed Matter Physics
Mechanical Engineering

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10.1299/kikaib.72.2109

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AU - Suzuki, Yukihito

AU - Koishikawa, Masaki

AU - Koshizuka, Seiichi

AU - Okamoto, Takuji

AU - Kaneko, Naotsugu

AU - Takamatsu, Atsuko

AU - Fujii, Teruo

PY - 2006/9

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N2 - The MPS method is a particle method which simulates motion of continua with a finite number of particles. Thus it is relatively easy to simulate complex flows such as those in a bioreactor in which the geometry of flow is continuously modified by adhesion of cells. In this study, flows with adhesion of cells in a micro channel are simulated using the MPS method. The adhesion pattern of cells is well reproduced by the simulation.

AB - The MPS method is a particle method which simulates motion of continua with a finite number of particles. Thus it is relatively easy to simulate complex flows such as those in a bioreactor in which the geometry of flow is continuously modified by adhesion of cells. In this study, flows with adhesion of cells in a micro channel are simulated using the MPS method. The adhesion pattern of cells is well reproduced by the simulation.

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KW - Computational fluid dynamics

KW - Micro flow

KW - Particle method

KW - Viscous flow

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JO - Nihon Kikai Gakkai Ronbunshu, B Hen/Transactions of the Japan Society of Mechanical Engineers, Part B

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Numerical simulation of adhesion of cells in micro channels using the MPS method

Abstract

Keywords

ASJC Scopus subject areas

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