TY - JOUR
T1 - Odor responses and spontaneous oscillatory activity in tentacular nerves of the terrestrial slug, Limax marginatus
AU - Ito, Iori
AU - Kimura, Tetsuya
AU - Ito, Etsuro
N1 - Funding Information:
We thank Dr Alan Gelperin for his helpful comments on the manuscript. This work was supported in part by Research Fellowship (No. 05725) of the Japan Society for the Promotion of Science for Young Scientists to I.I., Grants-in-Aid from the Ministry of Education, Culture, Sports, Science and Technology of Japan and by grants from Yamada Science Foundation and Itoh Science Foundation to E.I.
PY - 2001/5/25
Y1 - 2001/5/25
N2 - We studied the neural oscillatory activity in the peripheral olfactory system of the tentacles in the terrestrial slug, Limax marginatus, by extracellular recording. Recordings from the cut-ends of the inferior tentacular nerves connected to the inferior tentacular ganglia and sensory epithelia showed spontaneous oscillatory activity at frequencies of 0.1-30 Hz. This spontaneous activity was dominated by the 0.6-6 Hz band. Ethanol odor stimulation decreased the amplitude in the 0.6-6 Hz band and increased those in the 6-15 and 15-30 Hz bands. Antagonists of the γ-aminobutyric acid (GABA) receptor, bicuculline and picrotoxin, resulted in suppression of spontaneous activity and modulated the odor response in the 0.6-6 Hz band. Our results indicate the involvement of GABA-mediated oscillatory activity in the tentacular nerves in the olfactory processing in molluscs.
AB - We studied the neural oscillatory activity in the peripheral olfactory system of the tentacles in the terrestrial slug, Limax marginatus, by extracellular recording. Recordings from the cut-ends of the inferior tentacular nerves connected to the inferior tentacular ganglia and sensory epithelia showed spontaneous oscillatory activity at frequencies of 0.1-30 Hz. This spontaneous activity was dominated by the 0.6-6 Hz band. Ethanol odor stimulation decreased the amplitude in the 0.6-6 Hz band and increased those in the 6-15 and 15-30 Hz bands. Antagonists of the γ-aminobutyric acid (GABA) receptor, bicuculline and picrotoxin, resulted in suppression of spontaneous activity and modulated the odor response in the 0.6-6 Hz band. Our results indicate the involvement of GABA-mediated oscillatory activity in the tentacular nerves in the olfactory processing in molluscs.
KW - Bicuculline
KW - Invertebrate olfaction
KW - Local field potential
KW - Neural oscillation
KW - Picrotoxin
KW - γ-amino butyric acid
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U2 - 10.1016/S0304-3940(01)01775-X
DO - 10.1016/S0304-3940(01)01775-X
M3 - Article
C2 - 11343823
AN - SCOPUS:0035947216
SN - 0304-3940
VL - 304
SP - 145
EP - 148
JO - Neuroscience Letters
JF - Neuroscience Letters
IS - 3
ER -