Optimization of the energy window setting in Ir-192 source imaging for high-dose-rate brachytherapy using a YAP(Ce) gamma camera

Jura Nagata; Kohei Nakanishi; Seiichi Yamamoto; Takuya Yabe; Katsunori Yogo; Yumiko Noguchi; Kuniyasu Okudaira; Kei Kamada; Akira Yoshikawa; Jun Kataoka

doi:10.1016/j.ejmp.2022.09.017

Optimization of the energy window setting in Ir-192 source imaging for high-dose-rate brachytherapy using a YAP(Ce) gamma camera

Jura Nagata, Kohei Nakanishi, Seiichi Yamamoto^*, Takuya Yabe, Katsunori Yogo, Yumiko Noguchi, Kuniyasu Okudaira, Kei Kamada, Akira Yoshikawa, Jun Kataoka

^*Corresponding author for this work

Waseda Research Institute for Science and Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: Although real-time imaging of the high-activity iridium-192 (Ir-192) source position during high-dose-rate (HDR) brachytherapy using a high-energy gamma camera system is a promising approach, the energy window was not optimized for spatial resolution or scatter fraction. Methods: By using a list-mode data-acquisition system that can acquire energy information of a cerium-doped yttrium aluminum perovskite (YA1O₃: YAP(Ce)) gamma camera, we tried to optimize the energy window's setting to improve the spatial resolution and reduce scatter fraction. Results: The spatial resolution was highest for the central energy of the window at ∼300 keV. The scatter fraction was also smallest for the central energy of the window at ∼300 keV, and the scatter fraction was more than 48 % smaller than that for the full energy window. Conclusions: We clarified that the spatial resolution can be improved and the scatter fraction can be reduced through optimizing the energy window of the YAP(Ce) gamma camera by setting the central energy of the window to ∼300 keV for HDR brachytherapy.

Original language	English
Pages (from-to)	66-73
Number of pages	8
Journal	Physica Medica
Volume	103
DOIs	https://doi.org/10.1016/j.ejmp.2022.09.017
Publication status	Published - 2022 Nov

Keywords

Energy spectrum
HDR brachytherapy
Imaging
Ir-192 source
List mode
YAP(Ce)

ASJC Scopus subject areas

Biophysics
Radiology Nuclear Medicine and imaging
Physics and Astronomy(all)

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10.1016/j.ejmp.2022.09.017

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title = "Optimization of the energy window setting in Ir-192 source imaging for high-dose-rate brachytherapy using a YAP(Ce) gamma camera",

abstract = "Purpose: Although real-time imaging of the high-activity iridium-192 (Ir-192) source position during high-dose-rate (HDR) brachytherapy using a high-energy gamma camera system is a promising approach, the energy window was not optimized for spatial resolution or scatter fraction. Methods: By using a list-mode data-acquisition system that can acquire energy information of a cerium-doped yttrium aluminum perovskite (YA1O3: YAP(Ce)) gamma camera, we tried to optimize the energy window's setting to improve the spatial resolution and reduce scatter fraction. Results: The spatial resolution was highest for the central energy of the window at ∼300 keV. The scatter fraction was also smallest for the central energy of the window at ∼300 keV, and the scatter fraction was more than 48 % smaller than that for the full energy window. Conclusions: We clarified that the spatial resolution can be improved and the scatter fraction can be reduced through optimizing the energy window of the YAP(Ce) gamma camera by setting the central energy of the window to ∼300 keV for HDR brachytherapy.",

keywords = "Energy spectrum, HDR brachytherapy, Imaging, Ir-192 source, List mode, YAP(Ce)",

author = "Jura Nagata and Kohei Nakanishi and Seiichi Yamamoto and Takuya Yabe and Katsunori Yogo and Yumiko Noguchi and Kuniyasu Okudaira and Kei Kamada and Akira Yoshikawa and Jun Kataoka",

note = "Funding Information: This work was supported in part by JSPS KAKENHI Grant Number 19H00672. This work was also supported by JST ERATO Grant Number JPMJER2102, Japan. Publisher Copyright: {\textcopyright} 2022",

year = "2022",

month = nov,

doi = "10.1016/j.ejmp.2022.09.017",

language = "English",

volume = "103",

pages = "66--73",

journal = "Physica Medica",

issn = "1120-1797",

publisher = "Associazione Italiana di Fisica Medica",

}

TY - JOUR

T1 - Optimization of the energy window setting in Ir-192 source imaging for high-dose-rate brachytherapy using a YAP(Ce) gamma camera

AU - Nagata, Jura

AU - Nakanishi, Kohei

AU - Yamamoto, Seiichi

AU - Yabe, Takuya

AU - Yogo, Katsunori

AU - Noguchi, Yumiko

AU - Okudaira, Kuniyasu

AU - Kamada, Kei

AU - Yoshikawa, Akira

AU - Kataoka, Jun

PY - 2022/11

Y1 - 2022/11

N2 - Purpose: Although real-time imaging of the high-activity iridium-192 (Ir-192) source position during high-dose-rate (HDR) brachytherapy using a high-energy gamma camera system is a promising approach, the energy window was not optimized for spatial resolution or scatter fraction. Methods: By using a list-mode data-acquisition system that can acquire energy information of a cerium-doped yttrium aluminum perovskite (YA1O3: YAP(Ce)) gamma camera, we tried to optimize the energy window's setting to improve the spatial resolution and reduce scatter fraction. Results: The spatial resolution was highest for the central energy of the window at ∼300 keV. The scatter fraction was also smallest for the central energy of the window at ∼300 keV, and the scatter fraction was more than 48 % smaller than that for the full energy window. Conclusions: We clarified that the spatial resolution can be improved and the scatter fraction can be reduced through optimizing the energy window of the YAP(Ce) gamma camera by setting the central energy of the window to ∼300 keV for HDR brachytherapy.

AB - Purpose: Although real-time imaging of the high-activity iridium-192 (Ir-192) source position during high-dose-rate (HDR) brachytherapy using a high-energy gamma camera system is a promising approach, the energy window was not optimized for spatial resolution or scatter fraction. Methods: By using a list-mode data-acquisition system that can acquire energy information of a cerium-doped yttrium aluminum perovskite (YA1O3: YAP(Ce)) gamma camera, we tried to optimize the energy window's setting to improve the spatial resolution and reduce scatter fraction. Results: The spatial resolution was highest for the central energy of the window at ∼300 keV. The scatter fraction was also smallest for the central energy of the window at ∼300 keV, and the scatter fraction was more than 48 % smaller than that for the full energy window. Conclusions: We clarified that the spatial resolution can be improved and the scatter fraction can be reduced through optimizing the energy window of the YAP(Ce) gamma camera by setting the central energy of the window to ∼300 keV for HDR brachytherapy.

KW - Energy spectrum

KW - HDR brachytherapy

KW - Imaging

KW - Ir-192 source

KW - List mode

KW - YAP(Ce)

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ER -

Optimization of the energy window setting in Ir-192 source imaging for high-dose-rate brachytherapy using a YAP(Ce) gamma camera

Abstract

Keywords

ASJC Scopus subject areas

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