Optofluidic device for ultra-sensitive molecule detection using surfaceenhanced Raman spectroscopy

Miao Wang; Nan Jing; Melodie Benford; I. Hsien Chou; Hope T. Beier; Gerard L. Coté; Jun Kameoka

Optofluidic device for ultra-sensitive molecule detection using surfaceenhanced Raman spectroscopy

Miao Wang, Nan Jing, Melodie Benford, I. Hsien Chou, Hope T. Beier, Gerard L. Coté, Jun Kameoka

Research output: Contribution to conference › Paper › peer-review

Abstract

We have developed an optofluidic device that can significantly improve the sensitivity, efficiency and reproducibility of the surface enhanced Raman spectroscopy (SERS). This device has demonstrated the capalibity of detecting molecules of interest at ultra-low concentration and is able to identify fingerprint signals from multiple analytes. This device can potentially be used for the definitive early stage diagnostics of disease associated with protein conformation change such as Alzheimer's disease (AD) or Bovine Spongiform Encephalopathy (BSE) .

Original language	English
Pages	314-316
Number of pages	3
Publication status	Published - 2008
Externally published	Yes
Event	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: 2008 Oct 12 → 2008 Oct 16

Conference

Conference	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country/Territory	United States
City	San Diego, CA
Period	08/10/12 → 08/10/16

Keywords

Molecule detection
Optofluidic
Surface-enhanced Raman

ASJC Scopus subject areas

Chemical Engineering (miscellaneous)
Bioengineering

Cite this

Optofluidic device for ultra-sensitive molecule detection using surfaceenhanced Raman spectroscopy. / Wang, Miao; Jing, Nan; Benford, Melodie et al.
2008. 314-316 Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.

Research output: Contribution to conference › Paper › peer-review

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abstract = "We have developed an optofluidic device that can significantly improve the sensitivity, efficiency and reproducibility of the surface enhanced Raman spectroscopy (SERS). This device has demonstrated the capalibity of detecting molecules of interest at ultra-low concentration and is able to identify fingerprint signals from multiple analytes. This device can potentially be used for the definitive early stage diagnostics of disease associated with protein conformation change such as Alzheimer's disease (AD) or Bovine Spongiform Encephalopathy (BSE) .",

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language = "English",

pages = "314--316",

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T1 - Optofluidic device for ultra-sensitive molecule detection using surfaceenhanced Raman spectroscopy

AU - Wang, Miao

AU - Jing, Nan

AU - Benford, Melodie

AU - Chou, I. Hsien

AU - Beier, Hope T.

AU - Coté, Gerard L.

AU - Kameoka, Jun

PY - 2008

Y1 - 2008

N2 - We have developed an optofluidic device that can significantly improve the sensitivity, efficiency and reproducibility of the surface enhanced Raman spectroscopy (SERS). This device has demonstrated the capalibity of detecting molecules of interest at ultra-low concentration and is able to identify fingerprint signals from multiple analytes. This device can potentially be used for the definitive early stage diagnostics of disease associated with protein conformation change such as Alzheimer's disease (AD) or Bovine Spongiform Encephalopathy (BSE) .

AB - We have developed an optofluidic device that can significantly improve the sensitivity, efficiency and reproducibility of the surface enhanced Raman spectroscopy (SERS). This device has demonstrated the capalibity of detecting molecules of interest at ultra-low concentration and is able to identify fingerprint signals from multiple analytes. This device can potentially be used for the definitive early stage diagnostics of disease associated with protein conformation change such as Alzheimer's disease (AD) or Bovine Spongiform Encephalopathy (BSE) .

KW - Molecule detection

KW - Optofluidic

KW - Surface-enhanced Raman

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M3 - Paper

AN - SCOPUS:84902489739

SP - 314

EP - 316

T2 - 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008

Y2 - 12 October 2008 through 16 October 2008

ER -

Optofluidic device for ultra-sensitive molecule detection using surfaceenhanced Raman spectroscopy

Abstract

Conference

Keywords

ASJC Scopus subject areas

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