Organic-inorganic mesoporous nanocarriers integrated with biogenic ligands

Jinlou Gu*, Wei Fan, Atsushi Shimojima, Tatsuya Okubo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

113 Citations (Scopus)


A novel process for the synthesis of low-submicrometer organic-inorganic mesoporous nanoparticles (MNPs) with Brunauer-Emmett-Teller (BET) with high surface area and large pored volume was analyzed. Cetyltrimethylammonium bromide was dissolved in a solution that contained water and EG with ammonia aqueous solution. LA functionalization was activated by dicyclohexylcarbodiimide and N-hydroxysuccinimide dissolved in dimethylformamide solution with stirring. The generation of cylindrical micelles with a silicate coating (MSCs) initiated the nucleation involving surfactant-silicate interaction, which facilitated cylindrical, micelles with a silicate coating. Observation derived from the experiment implied that particle growth will be driven by surface area of contact between the particle and the surrounding fluid by forming the shape of sphere. The results show that the method is successful in the preparation of low submicrometer organic-inorganic hybrid MNPs.

Original languageEnglish
Pages (from-to)1740-1744
Number of pages5
Issue number10
Publication statusPublished - 2007 Oct
Externally publishedYes


  • Biomedicine
  • Hybrid materials
  • Mesoporous materials
  • Nanobiotechnology
  • Nanocarriers

ASJC Scopus subject areas

  • Biotechnology
  • Biomaterials
  • Chemistry(all)
  • Materials Science(all)


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