(Chemical Equation Presented) The trifluoroacetic acid salt of 2-(pyrrolidinylmethyl)pyrrolidine was found to be an effective organocatalyst of an asymmetric intramolecular aldol reaction, affording bicyclo[4.3.0]nonane derivatives with a high enantioselectivity, in which the rare combination of aldehyde as a nucleophile and ketone as an electrophile was realized.
|Number of pages||7|
|Journal||Journal of Organic Chemistry|
|Publication status||Published - 2007 Aug 17|
ASJC Scopus subject areas
- Organic Chemistry