TY - JOUR
T1 - Oxygen- and carbon monoxide-binding kinetic parameters for liposomal heme under semi-physiological condition
AU - Tsuchida, Eishun
AU - Nishide, Hiroyuki
AU - Sekine, Mikiya
AU - Yuasa, Makoto
AU - Iizuka, Tetsutaro
AU - Ishimura, Yuzuru
PY - 1982/12/15
Y1 - 1982/12/15
N2 - Binding and dissociation rate constants of oxygen and carbon monoxide with the meso-tetra(α,α,α,α-(o-pivalamidophenyl))porphinato iron-mono(1-lauryl-2-methylimidazole) complex incorporated into the liposomes of dimyristoylphosphatidylcholine (liposomal heme) were measured with flash-photolysis method at pH 7.0 and 20 °C. Extra large quantum yield was observed for the photo-dissociation of the oxygen adduct, while that for the CO adduct was relatively small. Rate constants for the binding and the dissociation were comparable to those of hemoglobin except for the oxygen-binding rate constant.
AB - Binding and dissociation rate constants of oxygen and carbon monoxide with the meso-tetra(α,α,α,α-(o-pivalamidophenyl))porphinato iron-mono(1-lauryl-2-methylimidazole) complex incorporated into the liposomes of dimyristoylphosphatidylcholine (liposomal heme) were measured with flash-photolysis method at pH 7.0 and 20 °C. Extra large quantum yield was observed for the photo-dissociation of the oxygen adduct, while that for the CO adduct was relatively small. Rate constants for the binding and the dissociation were comparable to those of hemoglobin except for the oxygen-binding rate constant.
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U2 - 10.1016/0006-291X(82)92019-8
DO - 10.1016/0006-291X(82)92019-8
M3 - Article
C2 - 7159447
AN - SCOPUS:0020455902
SN - 0006-291X
VL - 109
SP - 858
EP - 863
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 3
ER -