Patient-specific arterial fluid-structure interaction modeling of cerebral aneurysms

Kenji Takizawa, Creighton Moorman, Samuel Wright, John Purdue, Travis McPhail, Peng R. Chen, Joe Warren, Tayfun E. Tezduyar*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

78 Citations (Scopus)


We address the computational challenges related to the extraction of the arterial-lumen geometry, mesh generation and starting-point determination in the computation of arterial fluid-structure interactions (FSI) with patient-specific data. The methods we propose here to address those challenges include techniques for constructing suitable cutting planes at the artery inlets and outlets and specifying on those planes proper boundary conditions for the fluid mechanics, structural mechanics and fluid mesh motion and a technique for the improved calculation of an estimated zero-pressure arterial geometry. We use the stabilized space-time FSI technique, together with a number of special techniques recently developed for arterial FSI. We focus on three patient-specific cerebral artery segments with aneurysm, where the lumen geometries are extracted from 3D rotational angiography.

Original languageEnglish
Pages (from-to)308-323
Number of pages16
JournalInternational Journal for Numerical Methods in Fluids
Issue number1-3
Publication statusPublished - 2011 Jan
Externally publishedYes


  • Arterial fluid-structure interaction
  • Cerebral aneurysm
  • Estimated zero-pressure arterial geometry
  • Lumen-geometry extraction
  • Patient-specific data
  • Stabilized space-time FSI technique

ASJC Scopus subject areas

  • Computational Mechanics
  • Mechanics of Materials
  • Mechanical Engineering
  • Computer Science Applications
  • Applied Mathematics


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