PEDOT: TOS with PEG: A biofunctional surface with improved electronic characteristics

Leslie H. Jimison; Adel Hama; Xenofon Strakosas; Vanessa Armel; Dion Khodagholy; Esma Ismailova; George G. Malliaras; Bjorn Winther Jensen; Róisín M. Owens

doi:10.1039/c2jm32188b

PEDOT: TOS with PEG: A biofunctional surface with improved electronic characteristics

Leslie H. Jimison, Adel Hama, Xenofon Strakosas, Vanessa Armel, Dion Khodagholy, Esma Ismailova, George G. Malliaras, Bjorn Winther Jensen, Róisín M. Owens^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

Devices based on conducting polymers offer great promise for interfacing with cells. Here, we use vapour phase polymerisation to create a biofunctional composite material of the conducting polymer poly(3,4-ethylenedioxythiophene): tosylate (PEDOT:TOS) and the biologically relevant poly(ethylene glycol) (PEG). On the addition of PEG, electroactivity of the PEDOT is maintained, conductivity is increased, and its performance as the active material in a transistor is unaffected. Both direct and indirect biocompatibility tests prove that PEDOT:TOS and PEDOT:TOS:PEG are biocompatible and nontoxic to mammalian cells. A functionalised PEG (PEG(COOH)) was additionally introduced into PEDOT:TOS to showcase the potential of this material for use in applications requiring biofunctionalisation.

Original language	English
Pages (from-to)	19498-19505
Number of pages	8
Journal	Journal of Materials Chemistry
Volume	22
Issue number	37
DOIs	https://doi.org/10.1039/c2jm32188b
Publication status	Published - 2012 Oct 7
Externally published	Yes

ASJC Scopus subject areas

Materials Chemistry
Chemistry(all)

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abstract = "Devices based on conducting polymers offer great promise for interfacing with cells. Here, we use vapour phase polymerisation to create a biofunctional composite material of the conducting polymer poly(3,4-ethylenedioxythiophene): tosylate (PEDOT:TOS) and the biologically relevant poly(ethylene glycol) (PEG). On the addition of PEG, electroactivity of the PEDOT is maintained, conductivity is increased, and its performance as the active material in a transistor is unaffected. Both direct and indirect biocompatibility tests prove that PEDOT:TOS and PEDOT:TOS:PEG are biocompatible and nontoxic to mammalian cells. A functionalised PEG (PEG(COOH)) was additionally introduced into PEDOT:TOS to showcase the potential of this material for use in applications requiring biofunctionalisation.",

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T2 - TOS with PEG: A biofunctional surface with improved electronic characteristics

AU - Jimison, Leslie H.

AU - Hama, Adel

AU - Strakosas, Xenofon

AU - Armel, Vanessa

AU - Khodagholy, Dion

AU - Ismailova, Esma

AU - Malliaras, George G.

AU - Winther Jensen, Bjorn

AU - Owens, Róisín M.

PY - 2012/10/7

Y1 - 2012/10/7

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AB - Devices based on conducting polymers offer great promise for interfacing with cells. Here, we use vapour phase polymerisation to create a biofunctional composite material of the conducting polymer poly(3,4-ethylenedioxythiophene): tosylate (PEDOT:TOS) and the biologically relevant poly(ethylene glycol) (PEG). On the addition of PEG, electroactivity of the PEDOT is maintained, conductivity is increased, and its performance as the active material in a transistor is unaffected. Both direct and indirect biocompatibility tests prove that PEDOT:TOS and PEDOT:TOS:PEG are biocompatible and nontoxic to mammalian cells. A functionalised PEG (PEG(COOH)) was additionally introduced into PEDOT:TOS to showcase the potential of this material for use in applications requiring biofunctionalisation.

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PEDOT: TOS with PEG: A biofunctional surface with improved electronic characteristics

Abstract

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