Penasulfate A, a new α-glucosidase inhibitor from a marine sponge Penares sp.

Yoichi Nakao, Takashi Maki, Shigeki Matsunaga, Rob W.M. Van Soest, Nobuhiro Fusetani*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)

Abstract

A new α-glucosidase inhibitor, penasulfate A, has been isolated from a marine sponge Penares sp. Its structure was elucidated by spectral and chemical methods to be a scalemic mixture of methyl pipecolates acylated with a novel sulfated fatty acid.

Original languageEnglish
Pages (from-to)1346-1350
Number of pages5
JournalJournal of Natural Products
Volume67
Issue number8
DOIs
Publication statusPublished - 2004 Aug
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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