Photoactivation of cell adhesion on Caged Cell-Culturing Substrates: Effect of terminal functional groups on activation efficiency

Yukiko Kikuchi; Jun Nakanishi; Tohru Takarada; Hidekazu Nakayama; Kazuo Yamaguchi; Yasuhiko Yoshida; Mizuo Maeda

Photoactivation of cell adhesion on Caged Cell-Culturing Substrates: Effect of terminal functional groups on activation efficiency

Yukiko Kikuchi^*, Jun Nakanishi, Tohru Takarada, Hidekazu Nakayama, Kazuo Yamaguchi, Yasuhiko Yoshida, Mizuo Maeda

^*Corresponding author for this work

Research output: Contribution to conference › Paper › peer-review

Abstract

We have recently reported a "Caged Cell-Culturing Substrate", where cell adhesion can be switched on by UV illumination. The substrate is based on an alkylsiloxane terminating with a carboxyl group that is protected by a photocleavable 2-nitrobenzyl group. In the present study, we examined the effect of terminal functional groups on photoactivation of cell adhesion. Among four tested substrates terminating with different functional groups, the photoconversion of cell adhesion was the most effective on that terminating with an amino group.

Original language	English
Pages	2340
Number of pages	1
Publication status	Published - 2005
Externally published	Yes
Event	54th SPSJ Annual Meeting 2005 - Yokohama, Japan Duration: 2005 May 25 → 2005 May 27

Conference

Conference	54th SPSJ Annual Meeting 2005
Country/Territory	Japan
City	Yokohama
Period	05/5/25 → 05/5/27

Keywords

Caged compounds
Cell adhesion
Cell patterning
Monolayer
Photoswitching

ASJC Scopus subject areas

Engineering(all)

Cite this

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title = "Photoactivation of cell adhesion on Caged Cell-Culturing Substrates: Effect of terminal functional groups on activation efficiency",

abstract = "We have recently reported a {"}Caged Cell-Culturing Substrate{"}, where cell adhesion can be switched on by UV illumination. The substrate is based on an alkylsiloxane terminating with a carboxyl group that is protected by a photocleavable 2-nitrobenzyl group. In the present study, we examined the effect of terminal functional groups on photoactivation of cell adhesion. Among four tested substrates terminating with different functional groups, the photoconversion of cell adhesion was the most effective on that terminating with an amino group.",

keywords = "Caged compounds, Cell adhesion, Cell patterning, Monolayer, Photoswitching",

author = "Yukiko Kikuchi and Jun Nakanishi and Tohru Takarada and Hidekazu Nakayama and Kazuo Yamaguchi and Yasuhiko Yoshida and Mizuo Maeda",

year = "2005",

language = "English",

pages = "2340",

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TY - CONF

T1 - Photoactivation of cell adhesion on Caged Cell-Culturing Substrates

T2 - 54th SPSJ Annual Meeting 2005

AU - Kikuchi, Yukiko

AU - Nakanishi, Jun

AU - Takarada, Tohru

AU - Nakayama, Hidekazu

AU - Yamaguchi, Kazuo

AU - Yoshida, Yasuhiko

AU - Maeda, Mizuo

PY - 2005

Y1 - 2005

N2 - We have recently reported a "Caged Cell-Culturing Substrate", where cell adhesion can be switched on by UV illumination. The substrate is based on an alkylsiloxane terminating with a carboxyl group that is protected by a photocleavable 2-nitrobenzyl group. In the present study, we examined the effect of terminal functional groups on photoactivation of cell adhesion. Among four tested substrates terminating with different functional groups, the photoconversion of cell adhesion was the most effective on that terminating with an amino group.

AB - We have recently reported a "Caged Cell-Culturing Substrate", where cell adhesion can be switched on by UV illumination. The substrate is based on an alkylsiloxane terminating with a carboxyl group that is protected by a photocleavable 2-nitrobenzyl group. In the present study, we examined the effect of terminal functional groups on photoactivation of cell adhesion. Among four tested substrates terminating with different functional groups, the photoconversion of cell adhesion was the most effective on that terminating with an amino group.

KW - Caged compounds

KW - Cell adhesion

KW - Cell patterning

KW - Monolayer

KW - Photoswitching

UR - http://www.scopus.com/inward/record.url?scp=33645640810&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645640810&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33645640810

SP - 2340

Y2 - 25 May 2005 through 27 May 2005

ER -

Photoactivation of cell adhesion on Caged Cell-Culturing Substrates: Effect of terminal functional groups on activation efficiency

Abstract

Conference

Keywords

ASJC Scopus subject areas

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