Pinnaic acid and tauropinnaic acid: Two novel fatty acids composing a 6-azaspiro[4.5]decane unit from the Okinawan bivalve Pinna muricata

Tong Chou; Makoto Kuramoto; Yuko Otani; Mayumi Shikano; Kazunaga Yazawa; Daisuke Uemura

doi:10.1016/0040-4039(96)00704-6

Pinnaic acid and tauropinnaic acid: Two novel fatty acids composing a 6-azaspiro[4.5]decane unit from the Okinawan bivalve Pinna muricata

Tong Chou, Makoto Kuramoto, Yuko Otani, Mayumi Shikano, Kazunaga Yazawa, Daisuke Uemura^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

119 Citations (Scopus)

Abstract

Two novel fatty acids with cPLA₂ inhibitory activity, pinnaic acid and tauro-pinnaic acid, were isolated from the Okinawan bivalve Pinna muricata. Their structures, including the relative stereochemistry at C5, C9, C13 and C14, were elucidated by extensive 2D NMR spectroscopic analysis.

Original language	English
Pages (from-to)	3871-3874
Number of pages	4
Journal	Tetrahedron Letters
Volume	37
Issue number	22
DOIs	https://doi.org/10.1016/0040-4039(96)00704-6
Publication status	Published - 1996 May
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Organic Chemistry
Drug Discovery

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10.1016/0040-4039(96)00704-6

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abstract = "Two novel fatty acids with cPLA2 inhibitory activity, pinnaic acid and tauro-pinnaic acid, were isolated from the Okinawan bivalve Pinna muricata. Their structures, including the relative stereochemistry at C5, C9, C13 and C14, were elucidated by extensive 2D NMR spectroscopic analysis.",

author = "Tong Chou and Makoto Kuramoto and Yuko Otani and Mayumi Shikano and Kazunaga Yazawa and Daisuke Uemura",

year = "1996",

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T2 - Two novel fatty acids composing a 6-azaspiro[4.5]decane unit from the Okinawan bivalve Pinna muricata

AU - Chou, Tong

AU - Kuramoto, Makoto

AU - Otani, Yuko

AU - Shikano, Mayumi

AU - Yazawa, Kazunaga

AU - Uemura, Daisuke

PY - 1996/5

Y1 - 1996/5

N2 - Two novel fatty acids with cPLA2 inhibitory activity, pinnaic acid and tauro-pinnaic acid, were isolated from the Okinawan bivalve Pinna muricata. Their structures, including the relative stereochemistry at C5, C9, C13 and C14, were elucidated by extensive 2D NMR spectroscopic analysis.

AB - Two novel fatty acids with cPLA2 inhibitory activity, pinnaic acid and tauro-pinnaic acid, were isolated from the Okinawan bivalve Pinna muricata. Their structures, including the relative stereochemistry at C5, C9, C13 and C14, were elucidated by extensive 2D NMR spectroscopic analysis.

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Pinnaic acid and tauropinnaic acid: Two novel fatty acids composing a 6-azaspiro[4.5]decane unit from the Okinawan bivalve Pinna muricata

Abstract

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