Potential response of monolayer-modified indium tin oxide electrodes to indole compounds

Takuya Nakanishi, Tsubasa Ueno, Mariko Matsunaga, Md Zaved Hossain Khan, Tetsuya Osaka*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Potential response of indium tin oxide (ITO) electrode modified by treatment with disuccinimidyl suberate (DSS) was investigated to various target molecules. Distinctively, the DSS-modified ITO electrode exhibited a potential shift to the molecules possessing an indole group such as tryptophan, tryptamine and indole propionic acid, while little response to benzoic acid, phenylalanine, proline, proline amide, and arginine was observed. In addition, the combination of this specificity to indoles and enantioselective affinity of human serum albumin (HSA), which was additionally immobilized on the DSS-modified ITO electrode, brought about enantioselective potential response to tryptophan.

Original languageEnglish
Pages (from-to)393-398
Number of pages6
Issue number4
Publication statusPublished - 2010 Feb


  • Chiral sensors
  • Indium tin oxide
  • Indole compounds
  • Monolayer modification
  • Potentiometric detection
  • Sensors

ASJC Scopus subject areas

  • Analytical Chemistry
  • Electrochemistry


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