Preparation of high-density thermo-responsive polymer grafted surfaces and their application in novel aqueous chromatography column packed materials

Aya Mizutami; Akihiko Kikuchi; Naokazu Idota; Jun Kobayashi; Kiyotaka Sakai; Hideko Kanazawa; Temo Okano

Preparation of high-density thermo-responsive polymer grafted surfaces and their application in novel aqueous chromatography column packed materials

Aya Mizutami^*, Akihiko Kikuchi, Naokazu Idota, Jun Kobayashi, Kiyotaka Sakai, Hideko Kanazawa, Temo Okano

^*Corresponding author for this work

Waseda Research Institute for Science and Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

In the present research, thermoresponsive surfaces grafted with high-density poly(N-isopropylacrylamide) (PIPAAm) are prepared by surface-initiated atom transfer radical polymerization (ATRP) on silica-based chromatography column packing materials. Prepared surfaces were analyzed in terms of surface elemental analyses and amount of the grafted polymers increased with increasing reaction time, indicating that reaction proceeds in living fashioa Thermoresponsive surface property alteration was also analyzed in hydrophobic chromatography of hydrophobic bioactive molecules under aqueous mobile phase.

Original language	English
Title of host publication	Polymer Preprints, Japan
Pages	2256
Number of pages	1
Volume	54
Edition	1
Publication status	Published - 2005
Event	54th SPSJ Annual Meeting 2005 - Yokohama Duration: 2005 May 25 → 2005 May 27

Other

Other	54th SPSJ Annual Meeting 2005
City	Yokohama
Period	05/5/25 → 05/5/27

Keywords

Chromatography matrices
High-density polymer grafted surfaces
Poly(N-isopropylacrylamide)
Surface-initiated atom transfer radical polymerization
Thermoresponsive polymer

ASJC Scopus subject areas

Engineering(all)

Cite this

@inproceedings{261f66d4985f44da91f1cee61e6c09f2,

title = "Preparation of high-density thermo-responsive polymer grafted surfaces and their application in novel aqueous chromatography column packed materials",

abstract = "In the present research, thermoresponsive surfaces grafted with high-density poly(N-isopropylacrylamide) (PIPAAm) are prepared by surface-initiated atom transfer radical polymerization (ATRP) on silica-based chromatography column packing materials. Prepared surfaces were analyzed in terms of surface elemental analyses and amount of the grafted polymers increased with increasing reaction time, indicating that reaction proceeds in living fashioa Thermoresponsive surface property alteration was also analyzed in hydrophobic chromatography of hydrophobic bioactive molecules under aqueous mobile phase.",

keywords = "Chromatography matrices, High-density polymer grafted surfaces, Poly(N-isopropylacrylamide), Surface-initiated atom transfer radical polymerization, Thermoresponsive polymer",

author = "Aya Mizutami and Akihiko Kikuchi and Naokazu Idota and Jun Kobayashi and Kiyotaka Sakai and Hideko Kanazawa and Temo Okano",

year = "2005",

language = "English",

volume = "54",

pages = "2256",

booktitle = "Polymer Preprints, Japan",

edition = "1",

note = "54th SPSJ Annual Meeting 2005 ; Conference date: 25-05-2005 Through 27-05-2005",

}

TY - GEN

T1 - Preparation of high-density thermo-responsive polymer grafted surfaces and their application in novel aqueous chromatography column packed materials

AU - Mizutami, Aya

AU - Kikuchi, Akihiko

AU - Idota, Naokazu

AU - Kobayashi, Jun

AU - Sakai, Kiyotaka

AU - Kanazawa, Hideko

AU - Okano, Temo

PY - 2005

Y1 - 2005

N2 - In the present research, thermoresponsive surfaces grafted with high-density poly(N-isopropylacrylamide) (PIPAAm) are prepared by surface-initiated atom transfer radical polymerization (ATRP) on silica-based chromatography column packing materials. Prepared surfaces were analyzed in terms of surface elemental analyses and amount of the grafted polymers increased with increasing reaction time, indicating that reaction proceeds in living fashioa Thermoresponsive surface property alteration was also analyzed in hydrophobic chromatography of hydrophobic bioactive molecules under aqueous mobile phase.

AB - In the present research, thermoresponsive surfaces grafted with high-density poly(N-isopropylacrylamide) (PIPAAm) are prepared by surface-initiated atom transfer radical polymerization (ATRP) on silica-based chromatography column packing materials. Prepared surfaces were analyzed in terms of surface elemental analyses and amount of the grafted polymers increased with increasing reaction time, indicating that reaction proceeds in living fashioa Thermoresponsive surface property alteration was also analyzed in hydrophobic chromatography of hydrophobic bioactive molecules under aqueous mobile phase.

KW - Chromatography matrices

KW - High-density polymer grafted surfaces

KW - Poly(N-isopropylacrylamide)

KW - Surface-initiated atom transfer radical polymerization

KW - Thermoresponsive polymer

UR - http://www.scopus.com/inward/record.url?scp=33645637231&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645637231&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:33645637231

VL - 54

SP - 2256

BT - Polymer Preprints, Japan

T2 - 54th SPSJ Annual Meeting 2005

Y2 - 25 May 2005 through 27 May 2005

ER -

Preparation of high-density thermo-responsive polymer grafted surfaces and their application in novel aqueous chromatography column packed materials

Abstract

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Keywords

ASJC Scopus subject areas

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