Prevalence of fatigue symptoms and correlations in the general adult population

Sayaka Aritake, Yoshitaka Kaneita*, Tadahiro Ohtsu, Makoto Uchiyama, Kazuo Mishima, Tsuneto Akashiba, Naohisa Uchimura, Shigeyuki Nakaji, Takeshi Munezawa, Takashi Ohida

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


This study sought to clarify the prevalence and associated factors of subjective fatigue symptoms, by analyzing epidemiological data for a sample of the Japanese population. Data from 1224 individuals (539 men and 685 women) aged ≥20 years were subsequently analyzed. Prevalence of fatigability was 17.2% (n = 211) and that of residual fatigue was 13.6% (n = 167), with women showing significantly higher prevalence of both symptoms than men (fatigability: men 12.6% vs women 20.9%, χ<sup>2</sup> = 14.43, P = 0.001; residual fatigue: men 10.0% vs women 16.5%, P = 0.001). Multivariate logistic regression analyses revealed that being female, nonrestorative sleep, decreased quality of life, and stress showed significant positive associations with fatigability and residual fatigue. However, a significant positive association was found between depressed mood and fatigability, and short sleep duration and long working hours (≥9h) were specifically significantly positively associated with residual fatigue. Sleep hygiene instruction and a psychiatric approach are needed to reduce fatigue in the Japanese population.

Original languageEnglish
Pages (from-to)146-154
Number of pages9
JournalSleep and Biological Rhythms
Issue number2
Publication statusPublished - 2015 Apr 1


  • Depression
  • Epidemiology
  • Fatigue
  • Japan
  • Quality of life
  • Sleep
  • Stress

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)
  • Neurology
  • Neuropsychology and Physiological Psychology


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