Production of eicosapentaenoic acid by marine bacteria

Kazunaga Yazawa*, Keiko Araki, Noriko Okazaki, Kazuo Watanabe, Chikako Ishikawa, Akira Inoue, Naganori Numao, Kiyosi Kondo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

76 Citations (Scopus)


About 5, 000 strains of marine microorganisms were screened for eicosapentaenoic acid (EPA)-producing ability, which was detected in 88 of them. All of the latter were found to be obligate aerobic, Gram-negative, motile, short rod-shaped bacteria. One strain, designated as SCRC-8132, showed a doubling time of 30 min at 25°C and produced 20 mg/ liter (4 mg/g dry cells) when cultured in a P-Y-M-Glucose medium for 18 h. The EPA to total fatty acids ratio was 24%. The strain produced 26 mg EPA/liter (15 mg/g dry cells) when cultured at 4°C for 5 days, the EPA ratio being increased to 40%.

Original languageEnglish
Pages (from-to)5-7
Number of pages3
JournalJournal of Biochemistry
Issue number1
Publication statusPublished - 1988 Jan
Externally publishedYes

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Molecular Biology
  • Biochemistry


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