TY - JOUR
T1 - Proposition of an outflow boundary approach for carotid artery stenosis CFD simulation
AU - Zhang, Yu
AU - Furusawa, Toyoki
AU - Sia, Sheau Fung
AU - Umezu, Mitsuo
AU - Qian, Yi
N1 - Funding Information:
This study was partially supported by the Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT); grant number A22591599, and Australian Research Council Linkage Grant; grant number LP0990263, C.I.: Y. Qian. We are also thankful to Mr Keith Ng for his contribution to this manuscript.
PY - 2013/5
Y1 - 2013/5
N2 - The purpose of this study was to propose an innovative approach of setting outlet boundary conditions for the computational fluid dynamics (CFD) simulation of human common carotid arteries (CCAs) bifurcation based on the concept of energy loss minimisation at flow bifurcation. Comparisons between this new approach and previously reported boundary conditions were also made. The results showed that CFD simulation based on the proposed boundary conditions gave an accurate prediction of the critical stenosis ratio of carotid arteries (at around 65%). Other boundary conditions, such as the constant external pressure (P = 0) and constant outflow ratio, either overestimated or underestimated the critical stenosis ratio of carotid arteries. The patient-specific simulation results furthermore indicated that the calculated internal carotid artery flow ratio at CCA bifurcation (61%) coincided with the result obtained by clinical measurements through the use of Colour Doppler ultrasound.
AB - The purpose of this study was to propose an innovative approach of setting outlet boundary conditions for the computational fluid dynamics (CFD) simulation of human common carotid arteries (CCAs) bifurcation based on the concept of energy loss minimisation at flow bifurcation. Comparisons between this new approach and previously reported boundary conditions were also made. The results showed that CFD simulation based on the proposed boundary conditions gave an accurate prediction of the critical stenosis ratio of carotid arteries (at around 65%). Other boundary conditions, such as the constant external pressure (P = 0) and constant outflow ratio, either overestimated or underestimated the critical stenosis ratio of carotid arteries. The patient-specific simulation results furthermore indicated that the calculated internal carotid artery flow ratio at CCA bifurcation (61%) coincided with the result obtained by clinical measurements through the use of Colour Doppler ultrasound.
KW - carotid artery stenosis
KW - cerebralvascular flows
KW - computational fluid dynamics
KW - energy loss
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U2 - 10.1080/10255842.2011.625358
DO - 10.1080/10255842.2011.625358
M3 - Article
C2 - 22288780
AN - SCOPUS:84878118779
SN - 1025-5842
VL - 16
SP - 488
EP - 494
JO - Computer Methods in Biomechanics and Biomedical Engineering
JF - Computer Methods in Biomechanics and Biomedical Engineering
IS - 5
ER -