TY - JOUR
T1 - Pyrizomicin A and B
T2 - Structure and bioactivity of new thiazolyl pyridines from Lechevalieria aerocolonigenes K10-0216
AU - Kimura, Toru
AU - Inahashi, Yuki
AU - Matsuo, Hirotaka
AU - Suga, Takuya
AU - Iwatsuki, Masato
AU - Shiomi, Kazuro
AU - Takahashi, Yoko
AU - Omura, Satoshi
AU - Nakashima, Takuji
N1 - Funding Information:
Funding This study was supported by funding from the Institute for Fermentation, Osaka (IFO), Japan.
Publisher Copyright:
© 2018 The Author(s) under exclusive licence to the Japan Antibiotics Research Association.
PY - 2018/6/1
Y1 - 2018/6/1
N2 - Two new antibiotics, designated pyrizomicin A and B, were isolated from the cultured broth of a rare actinomycete strain, Lechevalieria aerocolonigenes K10-0216, by silica gel and HPLC purification. The chemical structures of pyrizomicin A and B were elucidated as new thiazolyl pyridine compounds by nuclear magnetic resonance and mass spectrometry. Pyrizomicin A and B both showed antimicrobial activity.
AB - Two new antibiotics, designated pyrizomicin A and B, were isolated from the cultured broth of a rare actinomycete strain, Lechevalieria aerocolonigenes K10-0216, by silica gel and HPLC purification. The chemical structures of pyrizomicin A and B were elucidated as new thiazolyl pyridine compounds by nuclear magnetic resonance and mass spectrometry. Pyrizomicin A and B both showed antimicrobial activity.
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U2 - 10.1038/s41429-018-0038-y
DO - 10.1038/s41429-018-0038-y
M3 - Article
C2 - 29515230
AN - SCOPUS:85042917656
SN - 0021-8820
VL - 71
SP - 606
EP - 608
JO - Journal of Antibiotics
JF - Journal of Antibiotics
IS - 6
ER -