TY - JOUR
T1 - Rearrangement of hollow fibers for enhancing oxygen transfer in an artificial gill using oxygen carrier solution
AU - Nagase, Kenichi
AU - Kohori, Fukashi
AU - Sakai, Kiyotaka
AU - Nishide, Hiroyuki
N1 - Funding Information:
The authors wish to thank Dr. Akihiro C. Yamashita for useful suggestion. The authors also wish to thank Senko Medical Instrument Mfg. for supplying a membrane oxygenator and helpful discussion. This research was partially supported by the 21COE program “Practical Nano-Chemistry” from MEXT, Japan. This research was also partially supported by the Grant-in-Aid for Scientific Research (No. 16560685) from MEXT, Japan.
PY - 2005/6/1
Y1 - 2005/6/1
N2 - Using the derived mass transfer correlations for hollow fibers, hollow fiber arrangements were optimized for an artificial gill that uses an oxygen carrier solution. FC-40, a perfluorocarbon (PFC), was used as the oxygen carrier solution. In the oxygen uptake module, a hollow fiber arrangement with parallel coiled hollow fibers is preferred. The optimum outside diameter of the hollow fibers and the transverse pitch between them are 300 and 500 μm, respectively. In the oxygen release module, a hollow fiber arrangement of straight parallel hollow fibers is preferred. The optimum outside diameter of the hollow fibers and transverse pitch between them are 300 and 500 μm, respectively. In the case of humans, the scaling up was estimated from the oxygen transfer rates using these optimum hollow fiber arrangements. The required total membrane surface area is 50.8 m2, the total delivered pumping energy is 124 W, and the oxygen partial pressure in inspiration is 17.8 kPa. Importantly, the total membrane surface area required was significantly reduced using the modules with an optimum hollow fiber arrangement in comparison with that using connected membrane oxygenators as a gas exchanger. The optimization of hollow fiber arrangements in an artificial gill significantly enhances oxygen transfer from water to air.
AB - Using the derived mass transfer correlations for hollow fibers, hollow fiber arrangements were optimized for an artificial gill that uses an oxygen carrier solution. FC-40, a perfluorocarbon (PFC), was used as the oxygen carrier solution. In the oxygen uptake module, a hollow fiber arrangement with parallel coiled hollow fibers is preferred. The optimum outside diameter of the hollow fibers and the transverse pitch between them are 300 and 500 μm, respectively. In the oxygen release module, a hollow fiber arrangement of straight parallel hollow fibers is preferred. The optimum outside diameter of the hollow fibers and transverse pitch between them are 300 and 500 μm, respectively. In the case of humans, the scaling up was estimated from the oxygen transfer rates using these optimum hollow fiber arrangements. The required total membrane surface area is 50.8 m2, the total delivered pumping energy is 124 W, and the oxygen partial pressure in inspiration is 17.8 kPa. Importantly, the total membrane surface area required was significantly reduced using the modules with an optimum hollow fiber arrangement in comparison with that using connected membrane oxygenators as a gas exchanger. The optimization of hollow fiber arrangements in an artificial gill significantly enhances oxygen transfer from water to air.
KW - Artificial gill
KW - Fiber membranes
KW - Gas separation
KW - Modules
KW - Oxygen transfer
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U2 - 10.1016/j.memsci.2005.01.008
DO - 10.1016/j.memsci.2005.01.008
M3 - Article
AN - SCOPUS:18844460935
SN - 0376-7388
VL - 254
SP - 207
EP - 217
JO - Journal of Membrane Science
JF - Journal of Membrane Science
IS - 1-2
ER -