Reentrant conformational transitions in DNA molecules complexed with cationic surfactant

S. V. Mikhailenko; V. G. Sergeyev; K. Yoshikawa

Reentrant conformational transitions in DNA molecules complexed with cationic surfactant

S. V. Mikhailenko^*, V. G. Sergeyev, K. Yoshikawa

^*Corresponding author for this work

Research output: Contribution to conference › Paper › peer-review

Abstract

We have established the conditions for the dissociation-formation of DNA-CTAB complexes in organic solvents of different polarity. Fluorescence microscopy and CD spectroscopy indicate that DNA-CTAB complexes dissociate into their initial components at intermediate concentrations of alcohol, while conserving the double-stranded structure of native DNA. A further increase in the alcohol concentration leads to restoration of the complex, which is soluble under these conditions, i.e. in low-polarity organic media. As a novel phenomenon on DNA-CTAB interacting system, we have found the alcohol-induced reentrant globule-coil-globule transition in T4DNA-CTAB complexes.

Original language	English
Pages	213-215
Number of pages	3
Publication status	Published - 1998 Dec 1
Externally published	Yes
Event	Proceedings of the 1998 9th International Symposium on Micromechatronics and Human Science, MHS - Nagoya, Jpn Duration: 1998 Nov 25 → 1998 Nov 28

Other

Other	Proceedings of the 1998 9th International Symposium on Micromechatronics and Human Science, MHS
City	Nagoya, Jpn
Period	98/11/25 → 98/11/28

ASJC Scopus subject areas

Engineering(all)

Cite this

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title = "Reentrant conformational transitions in DNA molecules complexed with cationic surfactant",

abstract = "We have established the conditions for the dissociation-formation of DNA-CTAB complexes in organic solvents of different polarity. Fluorescence microscopy and CD spectroscopy indicate that DNA-CTAB complexes dissociate into their initial components at intermediate concentrations of alcohol, while conserving the double-stranded structure of native DNA. A further increase in the alcohol concentration leads to restoration of the complex, which is soluble under these conditions, i.e. in low-polarity organic media. As a novel phenomenon on DNA-CTAB interacting system, we have found the alcohol-induced reentrant globule-coil-globule transition in T4DNA-CTAB complexes.",

author = "Mikhailenko, {S. V.} and Sergeyev, {V. G.} and K. Yoshikawa",

year = "1998",

month = dec,

day = "1",

language = "English",

pages = "213--215",

note = "Proceedings of the 1998 9th International Symposium on Micromechatronics and Human Science, MHS ; Conference date: 25-11-1998 Through 28-11-1998",

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T1 - Reentrant conformational transitions in DNA molecules complexed with cationic surfactant

AU - Mikhailenko, S. V.

AU - Sergeyev, V. G.

AU - Yoshikawa, K.

PY - 1998/12/1

Y1 - 1998/12/1

N2 - We have established the conditions for the dissociation-formation of DNA-CTAB complexes in organic solvents of different polarity. Fluorescence microscopy and CD spectroscopy indicate that DNA-CTAB complexes dissociate into their initial components at intermediate concentrations of alcohol, while conserving the double-stranded structure of native DNA. A further increase in the alcohol concentration leads to restoration of the complex, which is soluble under these conditions, i.e. in low-polarity organic media. As a novel phenomenon on DNA-CTAB interacting system, we have found the alcohol-induced reentrant globule-coil-globule transition in T4DNA-CTAB complexes.

AB - We have established the conditions for the dissociation-formation of DNA-CTAB complexes in organic solvents of different polarity. Fluorescence microscopy and CD spectroscopy indicate that DNA-CTAB complexes dissociate into their initial components at intermediate concentrations of alcohol, while conserving the double-stranded structure of native DNA. A further increase in the alcohol concentration leads to restoration of the complex, which is soluble under these conditions, i.e. in low-polarity organic media. As a novel phenomenon on DNA-CTAB interacting system, we have found the alcohol-induced reentrant globule-coil-globule transition in T4DNA-CTAB complexes.

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M3 - Paper

AN - SCOPUS:0032316583

SP - 213

EP - 215

T2 - Proceedings of the 1998 9th International Symposium on Micromechatronics and Human Science, MHS

Y2 - 25 November 1998 through 28 November 1998

ER -

Reentrant conformational transitions in DNA molecules complexed with cationic surfactant

Abstract

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ASJC Scopus subject areas

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