Regionally specific occurrence of an active sodefrin variant in the red-bellied newt

Takeo Iwata; Yoko Ishizuka; Tomoaki Nakada; Fumiyo Toyoda; Kazutoshi Yamamoto; John M. Conlon; Sakae Kikuyama

doi:10.1196/annals.1327.059

Regionally specific occurrence of an active sodefrin variant in the red-bellied newt

Takeo Iwata, Yoko Ishizuka, Tomoaki Nakada, Fumiyo Toyoda, Kazutoshi Yamamoto, John M. Conlon, Sakae Kikuyama^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Sodefrin (SIPSKDALLK) is a female-attracting pheromone that is secreted by the abdominal gland of the male red-bellied newt. We found that mRNA encoding a sodefrin variant, [Val⁸] sodefrin, is expressed exclusively in specimens captured in the Nara area of Japan. The synthetic peptide was tested for its activity. It attracted females from Nara, but not those from other regions, suggesting that there is a geographic variation in the pheromone molecule and in the responsiveness to the pheromone. Employing an abdominal gland extract and synthetic substrates, the possibility of generation of the putative pheromone, [Val⁸] sodefrin, from the precursor molecule was demonstrated.

Original language	English
Pages (from-to)	351-353
Number of pages	3
Journal	Annals of the New York Academy of Sciences
Volume	1040
DOIs	https://doi.org/10.1196/annals.1327.059
Publication status	Published - 2005

Keywords

Female-attracting pheromone
processing
Sodefrin
Variant

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
History and Philosophy of Science

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10.1196/annals.1327.059

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title = "Regionally specific occurrence of an active sodefrin variant in the red-bellied newt",

abstract = "Sodefrin (SIPSKDALLK) is a female-attracting pheromone that is secreted by the abdominal gland of the male red-bellied newt. We found that mRNA encoding a sodefrin variant, [Val8] sodefrin, is expressed exclusively in specimens captured in the Nara area of Japan. The synthetic peptide was tested for its activity. It attracted females from Nara, but not those from other regions, suggesting that there is a geographic variation in the pheromone molecule and in the responsiveness to the pheromone. Employing an abdominal gland extract and synthetic substrates, the possibility of generation of the putative pheromone, [Val8] sodefrin, from the precursor molecule was demonstrated.",

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T1 - Regionally specific occurrence of an active sodefrin variant in the red-bellied newt

AU - Iwata, Takeo

AU - Ishizuka, Yoko

AU - Nakada, Tomoaki

AU - Toyoda, Fumiyo

AU - Yamamoto, Kazutoshi

AU - Conlon, John M.

AU - Kikuyama, Sakae

PY - 2005

Y1 - 2005

N2 - Sodefrin (SIPSKDALLK) is a female-attracting pheromone that is secreted by the abdominal gland of the male red-bellied newt. We found that mRNA encoding a sodefrin variant, [Val8] sodefrin, is expressed exclusively in specimens captured in the Nara area of Japan. The synthetic peptide was tested for its activity. It attracted females from Nara, but not those from other regions, suggesting that there is a geographic variation in the pheromone molecule and in the responsiveness to the pheromone. Employing an abdominal gland extract and synthetic substrates, the possibility of generation of the putative pheromone, [Val8] sodefrin, from the precursor molecule was demonstrated.

AB - Sodefrin (SIPSKDALLK) is a female-attracting pheromone that is secreted by the abdominal gland of the male red-bellied newt. We found that mRNA encoding a sodefrin variant, [Val8] sodefrin, is expressed exclusively in specimens captured in the Nara area of Japan. The synthetic peptide was tested for its activity. It attracted females from Nara, but not those from other regions, suggesting that there is a geographic variation in the pheromone molecule and in the responsiveness to the pheromone. Employing an abdominal gland extract and synthetic substrates, the possibility of generation of the putative pheromone, [Val8] sodefrin, from the precursor molecule was demonstrated.

KW - Female-attracting pheromone

KW - processing

KW - Sodefrin

KW - Variant

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Regionally specific occurrence of an active sodefrin variant in the red-bellied newt

Abstract

Keywords

ASJC Scopus subject areas

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