Regulation of chromatin structure by curved DNA: How activator binding sites become accessible

Takashi Ohyama

doi:10.1007/978-4-431-30130-1_10

Regulation of chromatin structure by curved DNA: How activator binding sites become accessible

Takashi Ohyama^*

^*Corresponding author for this work

School of Education

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

A single somatic cell of humans contains DNA fibers of a total length of approximately 2 m, which are compacted, without entanglement, into the nucleus of approximately 1×10^-5 m in diameter. To greater or lesser degrees, all organisms compact their DNA. Biologically important DNA regions, such as the origins of DNA replication, regulatory regions of transcription, and recombination loci, must all be compacted. The tightly constrained DNA, however, presents the appropriate environment for replication, transcription, and recombination to take place.

Original language	English
Title of host publication	Nuclear Dynamics
Subtitle of host publication	Molecular Biology and Visualization of the Nucleus
Publisher	Springer Japan
Pages	227-238
Number of pages	12
ISBN (Electronic)	9784431301301
ISBN (Print)	4431300546, 9784431300540
DOIs	https://doi.org/10.1007/978-4-431-30130-1_10
Publication status	Published - 2007 Jan 1

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1007/978-4-431-30130-1_10

Cite this

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Regulation of chromatin structure by curved DNA: How activator binding sites become accessible

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ASJC Scopus subject areas

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