Relation between sleep quality and physical activity in chronic heart failure patients

Kazuhiro P. Izawa, Satoshi Watanabe, Koichiro Oka, Koji Hiraki, Yuji Morio, Yusuke Kasa-hara, Naoya Takeichi, Takae Tsukamoto, Naohiko Osada, Kazuto Omiya, Haruo Makuuchi

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


To determine self-reported sleep quality-related differences in physical activity (PA) and health-related quality of life (HRQOL) and target values of PA for high-quality sleep in chronic heart failure (CHF) outpatients, 149 CHF outpatients (mean age 58 years) were divided into two groups by sleep-quality level determined via self-reported questionnaire: shallow sleep (SS) group (n = 77) and deep sleep (DS) group (n = 72). Steps were assessed by electronic pedometer, HRQOL was assessed with the Short Form 36 (SF-36) survey, and data were compared between groups. PA resulting in high-quality sleep was determined by receiver-operating characteristics curves. All SF-36 subscale scores except that of bodily pain were significantly decreased in the SS versus DS group. A cutoff value of 5723.6 steps/day and 156.4 Kcal/day for 1 week were determined as target values for PA. Sleep quality may affect PA and HRQOL, and attaining target values of PA may improve sleep quality and HRQOL of CHF outpatients. Patents relevant to heart failure are also discussed in this article.

Original languageEnglish
Pages (from-to)161-167
Number of pages7
JournalRecent Patents on Cardiovascular Drug Discovery
Issue number3
Publication statusPublished - 2011 Sept


  • Chronic heart failure
  • Health-related quality of life
  • Physical activity
  • Self-reported sleep quality

ASJC Scopus subject areas

  • Drug Discovery
  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)


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