Relationships between birth weight and serum cholesterol levels in healthy Japanese late adolescents

Sanae Ito, Kazuhiro Uenishi, Hiromi Ishida, Yukari Uemura, Momoko Kodama, Hideoki Fukuoka

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Poor growth in utero has been suggested to be associated with adverse levels of serum cholesterol concentrations in later life. In Asia, there have only been a limited number of studies examining the relationship between fetal status and serum lipids, especially in adolescents. The objective of this study was to examine the relationships between birth weight and serum high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol levels; adjusting for current physical status including percent body fat, physical activity and nutrient intake in healthy Japanese late adolescents. The data of 573 late adolescents with an average age of 17.6 (287 boys and 286 girls) who underwent physical examinations which included blood sampling and who had all the required data, were analyzed. Birth weight was obtained from their maternal and child health handbook. Multiple regression analysis showed that birth weight was positively associated with serum HDL in girls, independently of percent body fat or fat intake, when adjusted for current body height and weight. There were no associations between birth weight and serum HDL in boys, or serum LDL in either sex.

Original languageEnglish
Pages (from-to)108-113
Number of pages6
JournalJournal of Nutritional Science and Vitaminology
Issue number2
Publication statusPublished - 2014
Externally publishedYes


  • Birth weight
  • Body fat
  • Japanese late adolescent
  • Physical activity
  • Serum cholesterol

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


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