Abstract
RNA ligands (RNA aptamers) to a protease subtilisin were selected from pools of random RNA using SELEX (Systematic evolution of ligands by exponential enrichment). We selected RNA aptamers using a subtilisin-immobilized Sepharose column. After several rounds of selection, we obtained RNA aptamers that specifically inhibit the subtilisin activity. Characterization of the RNA aptamers will be reported.
| Original language | English |
|---|---|
| Pages (from-to) | 249-250 |
| Number of pages | 2 |
| Journal | Nucleic acids symposium series |
| Issue number | 37 |
| Publication status | Published - 1997 |
| Externally published | Yes |